Recent diabetes and weight loss linked to higher pancreatic cancer risk

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In a new study, researchers found that recently diagnosed diabetes accompanied by weight loss is linked to an increased risk for developing pancreatic cancer.

The research was conducted by a team at Dana-Farber Cancer Institute in Boston.

The team used data from 112,818 women participating in the Nurses’ Health Study and 46,207 men to evaluate the association of diabetes duration and recent weight change with the risk for pancreatic cancer.

The researchers found 1,116 incident cases of pancreatic cancer.

Participants with recently diagnosed diabetes had a higher risk for pancreatic cancer, as did those with long-standing diabetes, compared with participants without diabetes.

Participants who reported 1 to 4 pounds of weight loss had a higher risk for pancreatic cancer, as did those with 5 to 8 pounds of weight loss and those with more than an 8-pound weight loss compared with those with no weight loss.

Participants with recent diabetes plus weight loss of 1 to 8 pounds had still a higher risk, as did those with more than 8 pounds of weight loss compared with those with neither exposure.

The team says people with recently diagnosed diabetes accompanied by weight loss have a high risk for developing pancreatic cancer and may benefit from early detection strategies.

One author of the study is Chen Yuan, Sc.D.

The study is published in JAMA Oncology.

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