Scientists from Yale and other institutions have made a groundbreaking discovery in the fight against obesity.
They found that tirzepatide, a drug recently approved for treating type 2 diabetes, is also highly effective in reducing obesity.
Tirzepatide works by targeting two hormones that control blood sugar and signal fullness to the brain. Interestingly, people taking this drug for diabetes were also losing weight.
Focusing on individuals with obesity but without diabetes, the researchers discovered even more significant weight loss.
Those on the highest dose of the drug experienced dramatic reductions in body weight, with some losing as much as 21% of their body weight. This translates to a loss of 50-60 pounds for some individuals.
This result is notably more substantial than what’s been achieved with other obesity treatments, like semaglutide, which offers an average of up to about 15% weight loss.
Previous diet drugs only managed about a 5% weight reduction and often came with severe side effects.
The study found that most participants tolerated tirzepatide well. About 15% of those who received the drug dropped out of the 72-week trial, mainly due to gastrointestinal side effects. In comparison, 26% of participants who received a placebo dropped out.
The Food and Drug Administration (FDA) approved tirzepatide, marketed as Mounjaro, for type 2 diabetes treatment on May 13.
Researchers believe that this level of weight loss – 15% to over 20% – could redefine diabetes treatment, shifting the focus from simply controlling blood sugar to aiming for complete remission.
A previous study on tirzepatide in diabetes patients showed that half of the participants early in their diabetes course went into remission while on the drug.
For those interested in weight loss strategies, other studies have examined the unique benefits of certain exercises for weight loss and how specific eating habits might lead to excessive weight gain.
Additionally, for overall wellness, there are recent studies providing new exercise guidelines for people with type 2 diabetes and research indicating that vitamin D3 could help combat COVID-19 and other infections.
This research, led by Dr. Robert Gabbay and published in the New England Journal of Medicine, opens up new possibilities in obesity treatment, offering a more effective solution for significant weight loss.
This discovery is not just a win for those struggling with obesity, but also for those managing type 2 diabetes, potentially paving the way for a future where diabetes remission is a tangible goal.
If you care about diabetes, please read studies about new way to achieve type 2 diabetes remission, and one avocado a day keeps diabetes at bay.
For more information about diabetes, please see recent studies about 5 dangerous signs you have diabetes-related eye disease, and results showing why pomegranate is super fruit for people with diabetes.
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