Many people take dietary supplements like vitamins and minerals to support their health. However, a recent study from the University of Missouri suggests that taking high doses of nicotinamide riboside (NR), a form of vitamin B3, may increase the risk of serious diseases, including cancer.
NR has gained attention for its potential benefits related to heart health, metabolism, and brain function. However, this new study found that taking high levels of NR could increase the likelihood of developing triple-negative breast cancer, a particularly aggressive type of cancer.
Even more concerning, the research showed that NR might help cancer spread to the brain, where treatment options are extremely limited.
The researchers wanted to understand how NR, which helps increase cellular energy levels, might play a role in cancer growth. Since cancer cells require a lot of energy to grow and spread, they examined how NR was absorbed in cancer cells, immune cells (T cells), and healthy tissues.
Their findings suggest that high NR levels may unintentionally fuel cancer growth, making it easier for the disease to spread.
While the study raises concerns, more research is needed to fully understand the link between NR and cancer. The researchers hope their findings will help develop new treatments, including possible inhibitors that could block NR’s role in cancer metabolism.
However, because every cancer is different, treatments may need to be personalized. Cancer cells can also change how they use energy before or after treatments like chemotherapy, which adds another layer of complexity.
This study, led by Dr. Elena Goun, was published in Biosensors and Bioelectronics.
Choosing Dietary Supplements Wisely
The findings from this study highlight the importance of being cautious with dietary supplements. While supplements can support overall health, they may also have unintended side effects. Here are some tips to help you choose supplements safely:
- Consult a healthcare provider: Always check with your doctor before taking any supplement, especially if you have existing health conditions or take medications.
- Research the manufacturer: Not all supplement brands are trustworthy. Look for companies that follow good manufacturing practices and have a solid reputation.
- Check the label: Read the ingredients and dosage recommendations carefully. Avoid supplements with unclear ingredient lists.
- Look for third-party testing: Choose supplements that have been independently tested for purity and quality by organizations like NSF International, ConsumerLab.com, or USP.
- Be wary of “miracle cures”: If a supplement claims to cure or prevent serious diseases, it is likely making false or misleading claims.
- Stick to recommended dosages: Taking more than the suggested amount can be harmful and increase the risk of side effects.
- Don’t rely on supplements alone: A balanced diet, regular exercise, and a healthy lifestyle are the best ways to maintain good health. Supplements should only be used as an addition, not a replacement, for a healthy lifestyle.
While the potential risks of NR are still being studied, this research is a reminder that supplements should be used with caution. It’s always best to consult a healthcare professional before adding new supplements to your routine.
If you care about cancer, please read studies about vitamin D and bowel cancer, and a cautionary note about peanuts and cancer.
For more health information, please see recent studies about the link between ultra-processed foods and cancer, and everyday foods to ward off pancreatic cancer.
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