A recent study from the University of Missouri has raised concerns about the safety of high doses of nicotinamide riboside (NR), a form of vitamin B3 commonly found in dietary supplements.
This study contrasts with previous research suggesting NR’s benefits for heart, metabolic, and brain health.
The study indicates that high levels of NR might increase the risk of developing serious diseases, including triple-negative breast cancer.
More alarmingly, it suggests that NR could cause such cancers to metastasize or spread to the brain, a situation currently lacking effective treatment options.
The research team delved into NR’s role in energy production at a cellular level. Since cancer cells often thrive on this increased cellular energy, the study compared NR levels in cancer cells, T cells, and healthy tissues.
This approach was vital in understanding how NR might influence the growth and spread of cancer.
The findings underscore the necessity of thorough investigations into the potential side effects of dietary supplements like NR, particularly for individuals with various health conditions.
This is crucial as the metabolic profiles of cancers can differ significantly among individuals and may even change in response to treatments like chemotherapy.
Published in Biosensors and Bioelectronics by Elena Goun and colleagues, the study serves as a reminder of the complexity surrounding dietary supplements and their impact on health.
While the association between NR and an increased risk of serious diseases like cancer is concerning, more research is needed to confirm these findings and fully understand NR’s relationship with cancer.
In light of this, consulting a healthcare provider before taking any dietary supplements is always advisable.
Choosing Dietary Supplements Wisely
With a plethora of dietary supplements available, making informed choices can be challenging. Here are some guidelines to help:
- Consult Healthcare Providers: Before starting any supplement, discuss with healthcare providers to ensure safety and check for any potential interactions with current medications.
- Research the Manufacturer: Investigate the supplement manufacturer’s reputation and adherence to good manufacturing practices.
- Examine Labels Carefully: Check for clear information on ingredients, dosages, and possible side effects.
- Seek Third-Party Testing: Look for supplements tested by independent third parties like NSF International, ConsumerLab.com, or USP for quality assurance.
- Beware of Overhyped Claims: Be skeptical of supplements marketed as “miracle cures” or with claims of treating specific diseases.
- Adhere to Recommended Dosages: Overdosing can be harmful. Follow the label’s instructions or healthcare provider’s guidance.
- Complement, Don’t Substitute: Supplements should complement, not replace, a healthy diet and exercise regimen.
In summary, while dietary supplements can be beneficial, it’s crucial to approach them with caution, especially in light of recent findings like those regarding nicotinamide riboside.
As research evolves, staying informed and consulting healthcare professionals will help ensure safe and effective use of these supplements.
If you care about cancer, please read studies about Catching the silent killer: a new study on esophageal cancer and findings of New trick knocks out tough guy prostate cancer.
For more information about cancer, please see recent studies about How to harness the power of anti-cancer foods and supplements and results showing that Empower your plate: cancer-fighting foods and recipes.
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