In a new study, researchers found that exposure to high levels of oxygen encourages the brain to remain in deep, restorative sleep.
The new study was conducted by University of Alberta neuroscientists.
The researchers administered high levels of oxygen to anesthetized and naturally sleeping animal models, and examined the resulting activity in their brains.
They found that when we administer oxygen, our subjects’ brains switch out of active sleep, and remain in a deactivated, slow-wave state the entire time.
When they removed the oxygen, the brain started cycling back through active, or rapid-eye-movement, sleep again.
Deactivated or slow-wave sleep is the deepest stage of sleep, during which the brain oscillates at a very slow, once-per-second rhythm.
The team suggests that this seems to be the stage where metabolites are cleared from the brain, muscles grow, and proteins reform.
Slow-wave sleep seems to be especially suited to recovery for both the brain and body. Slow-wave sleep also plays a role in memory consolidation.
The researchers also showed that when exposed to less than normal levels of oxygen, the brain remains in active, or rapid-eye-movement (REM) sleep.
A rebound effect was found after the brain remained in REM sleep, in which the brain reverted to slow-wave sleep for a longer duration, as if it missed out on the slow-wave sleep during the activated stage.
The research highlights the potential for oxygen therapy for humans in a clinical setting.
The researchers suggest that oxygen therapy could be used to enhance slow-wave states during sleep to ensure that individuals who may have disrupted sleep are getting enough of the restorative, slow-wave sleep.
But this has to be tested first before this could become a therapeutic reality.
Brandon Hauer, PhD student in the neuroscience graduate program administered by the cross-faculty Neuroscience and Mental Health Institute, is one study researcher.
He conducted the research under the supervision of Professor Clay Dickson in the Department of Psychology.
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Source: University of Alberta.
