Scientists from the CDC found for males and females in all age groups, the risks for cardiac complications are higher after COVID-19 infection than after mRNA COVID-19 vaccination.
The research is published in Morbidity and Mortality Weekly Report and was conducted by Jason P. Block et al.
In the study, the team calculated the incidences of cardiac outcomes among people aged 5 years and older who had SARS-CoV-2 infection and after first, second, unspecified, or any dose of mRNA COVID-19 vaccine using electronic health record data from 40 U.S. health care systems.
They found that the highest incidence of cardiac outcomes after mRNA COVID-19 vaccination was seen in males aged 12 to 17 years after the second dose.
However, the risk for cardiac outcomes was 1.8 to 5.6 times as high after SARS-CoV-2 infection than after the second vaccine dose within this demographic group.
For all other groups, the risk for cardiac outcomes was much higher after SARS-CoV-2 infection than after the first, second, or unspecified dose of mRNA COVID-19 vaccination.
The findings suggest that cardiac complications were rare after SARS-CoV-2 infection or mRNA COVID-19 vaccination.
However, the risks for these complications were higher after infection than after vaccination among men and women in all age groups.
These findings provide important context for balancing the risks and benefits of mRNA COVID-19 vaccination among eligible persons ≥5 years.
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