Diabetes is a long-term health condition where the body can’t control the amount of sugar in the blood properly.
This can lead to serious health problems if it’s not managed well. Doctors often use medicine to help keep blood sugar levels under control. One of these medicines is called semaglutide.
A group of researchers, led by Dr. John Buse, wanted to find out if higher doses of semaglutide could help people with diabetes more than smaller doses.
They studied this by giving the drug to over 1,600 people with type 2 diabetes. Most of them were men around 58 years old. The study lasted for a year, and the results were published in a medical journal called The Lancet.
The participants were split into three groups. One group took 14 milligrams of semaglutide each day, another took 25 milligrams, and the third group took 50 milligrams. All of them had blood sugar levels that were too high at the start of the study.
Doctors checked their blood sugar using a test called A1C, which gives an average of a person’s blood sugar over several months. A healthy A1C level is below 7%.
At the beginning of the study, everyone had A1C levels between 8% and 10.5%, which means their diabetes was not well controlled. By the end of the study, more people in the 25 mg and 50 mg groups had reached healthy blood sugar levels compared to those in the 14 mg group. This means the higher doses worked better at helping people manage their diabetes.
But the good news doesn’t stop there. The medicine also helped people lose weight. This is important because many people with type 2 diabetes are overweight, and losing weight can make managing the disease easier.
After one year, people who took the highest dose—50 mg—lost about 17.5 pounds. Those who took 25 mg lost around 14.8 pounds, and the group that took 14 mg lost about 10 pounds.
Dr. Buse said that even the smaller dose does a good job of lowering blood sugar, but the higher doses are more helpful for losing weight. So, people who need help with both blood sugar and weight might benefit more from a higher dose.
However, like all medications, semaglutide can have side effects. The most common problems people reported were stomach-related. Some felt sick to their stomach, especially those on the higher doses. Others had diarrhea or constipation.
In conclusion, semaglutide is a helpful medicine for people with type 2 diabetes. It can lower blood sugar and help with weight loss. Higher doses seem to work better, especially for weight, but they can also cause more stomach issues. People should talk to their doctors to find the right dose for them.
If you care about diabetes, please read studies about bananas and diabetes, and honey could help control blood sugar.
For more health information, please see recent studies about Vitamin D that may reduce dangerous complications in diabetes and results showing plant-based protein foods may help reverse type 2 diabetes.
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