Popular blood pressure drugs cut risks even after mild heart attacks

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Heart attacks are one of the most serious medical emergencies a person can experience.

They happen when a blood clot blocks an artery that supplies blood to the heart, cutting off oxygen and causing damage to the heart muscle.

Symptoms often include chest pain, shortness of breath, and sudden weakness, and they require immediate hospital treatment.

Worldwide, cardiovascular disease is the leading cause of death, claiming nearly 20 million lives in 2022.

Of those deaths, 85 percent were linked to heart attacks and strokes. With numbers like these, doctors are constantly looking for the best ways to improve survival and prevent future complications.

One of the most common treatments after a heart attack is beta-blockers, a class of drugs that reduce strain on the heart.

These pills work by slowing the heart rate, lowering blood pressure, and decreasing the heart’s oxygen demand. They also help protect against dangerous irregular heart rhythms, known as arrhythmias.

Traditionally, beta-blockers have been given to patients whose heart muscle shows clear damage after a heart attack.

But until recently, doctors were unsure whether patients whose hearts function normally—or nearly normally—would benefit in the same way.

Some cardiologists questioned whether beta-blockers were still necessary for these patients, especially as treatments for heart attacks have advanced dramatically since the 1980s, when beta-blockers first became a standard therapy.

Now, two large international studies suggest that beta-blockers should be prescribed to all heart attack patients, regardless of how much damage their hearts sustained.

One of these studies, conducted in Norway and Denmark, followed 5,700 patients who had suffered an acute heart attack within the previous two weeks.

All had little or no heart muscle damage. Half of the patients were randomly assigned to receive the beta-blocker metoprolol, while the other half received standard treatment without beta-blockers.

The patients were followed closely for three and a half years. Researchers tracked who experienced another heart attack, developed heart failure, or suffered from arrhythmias. The results were clear: those who took beta-blockers had a lower risk of further heart problems. The protective effect was strongest among patients with minor damage to their heart muscle, but even patients with normal heart function benefitted.

“Our study shows that everyone with normal or only mildly reduced heart function should receive beta-blockers after a heart attack, just like patients with more obvious heart damage,” explained Professor John Munkhaugen, a cardiologist at Drammen Hospital in Norway.

These findings are expected to reshape international treatment guidelines. Professor Dan Atar, a cardiologist at Oslo University Hospital, emphasized that the results create a new knowledge base for heart attack care worldwide. “This could significantly influence treatment recommendations and improve outcomes for patients across the globe,” he said.

Further research is already underway to explore how factors like age, gender, and overall quality of life may influence the benefits of beta-blockers. Scientists also plan to study side effects such as sleep problems, sexual dysfunction, and mood changes, with the goal of fine-tuning care for individual patients.

For now, though, the message is straightforward: beta-blockers remain an essential tool for protecting the heart, and all patients recovering from a heart attack may benefit from their use—whether their hearts show damage or not.

If you care about heart health, please read studies that vitamin K helps cut heart disease risk by a third, and a year of exercise reversed worrisome heart failure.

For more health information, please see recent studies about supplements that could help prevent heart disease, stroke, and results showing this food ingredient may strongly increase heart disease death risk.

Source: University of Oslo.