Scientists find how to predict Alzheimer’s before symptoms start

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Imagine if doctors could tell who might get Alzheimer’s disease before any memory problems begin. That’s exactly what a team of researchers from Boston University is working on—and their new discovery could change how we fight this difficult illness.

Alzheimer’s is a disease that slowly damages the brain. People who have it begin to forget things, think less clearly, and often lose the ability to care for themselves. It’s a heartbreaking condition that affects not only those who have it, but also the people who care for them.

Around the world, millions of families face emotional stress, money problems, and health challenges because of Alzheimer’s. And with cases expected to rise, the cost of care could reach more than $1 trillion in just a few years.

One major challenge in stopping Alzheimer’s is that by the time someone shows clear signs of the disease, a lot of damage has already been done in the brain. Most treatments we have now are used too late to make a big difference.

That’s why early detection is so important—if we could identify who is at risk sooner, we might have a better chance to slow down or even stop the disease.

To tackle this, Dr. Vijaya B. Kolachalama and his team at Boston University came up with a new approach. They built a computer program designed to predict who might develop Alzheimer’s, even before symptoms show up. The tool uses a mix of medical knowledge and artificial intelligence to spot early warning signs in the brain.

Here’s how it works. The researchers used data from two large Alzheimer’s studies. They focused on people who had mild memory problems but had not yet been diagnosed with Alzheimer’s.

These people were grouped based on levels of a protein found in their brain fluid—a protein that often increases in Alzheimer’s. The team then looked at brain scans and other health data to see who went on to develop the disease.

Using all this information, the computer program was trained to recognize patterns. It could predict who would likely develop Alzheimer’s and even estimate when. The scientists compared the program’s results to expert opinions and to medical records collected later—even after some patients had passed away—and found their predictions were very accurate.

What’s even more impressive is that the program was able to highlight specific areas of the brain linked to Alzheimer’s. That means it wasn’t just guessing—it was learning from real medical clues. And because the program uses common tools like MRI scans and clear explanations of how it works, doctors can easily use it in real-world settings.

This kind of work shows how powerful it can be when technology and medicine come together. By combining computer science with brain research, the team has created a tool that could help doctors find people at risk much earlier than ever before.

The findings were published in the journal iScience, and they could lead to big improvements in how we treat and understand Alzheimer’s in the future. With early warning systems like this, doctors may one day offer support and care before the disease takes hold—giving people and families more time, more options, and more hope.

If you’re interested in brain health, other recent studies show that vitamin D deficiency and nighttime blood pressure problems may increase the risk of Alzheimer’s. Antioxidants and even some epilepsy drugs are also being studied as possible ways to reduce or treat the disease.

Every discovery brings us one step closer to better prevention—and maybe even a cure.

If you care about Alzheimer’s disease, please read studies about vitamin D deficiency linked to Alzheimer’s and dementia, and strawberries can be good defence against Alzheimer’s.

For more health information, please see recent studies about foods that reduce Alzheimer’s risk, and oral cannabis extract may help reduce Alzheimer’s symptoms.

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