A natural compound may extend life and prevent Alzheimer’s

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Researchers from the University of Seville in Spain, along with scientists from the University of Kent in the U.K., have made an exciting discovery that could impact health and longevity.

They found that a natural compound called phytoene, found in many fruits and vegetables, can extend the lifespan of a tiny organism called Caenorhabditis elegans and protect against symptoms related to Alzheimer’s disease.

Phytoene is a type of carotenoid, which is a natural pigment responsible for the bright colors of many fruits and vegetables. Some common foods rich in phytoene include tomatoes, carrots, apricots, red peppers, oranges, mandarins, and passion fruit. Carotenoids are not just known for their vibrant colors; they are also celebrated for their health benefits.

In the study, researchers discovered that phytoene increased the lifespan of Caenorhabditis elegans by 10% to 18.6%. This is a significant boost, considering the simple structure of the organism. Even more impressive, phytoene reduced the harmful effects of amyloid plaques—protein clumps linked to Alzheimer’s disease—by 30% to 40%.

The research was part of Ángeles Morón Ortiz’s doctoral studies and included testing both pure phytoene and extracts rich in phytoene from microalgae.

The results were published in the scientific journal Antioxidants, highlighting the promising health benefits of this natural compound. Now, the research team is seeking additional funding to explore how phytoene produces these protective effects.

Caenorhabditis elegans is a tiny worm often used in scientific research. Despite its simplicity, this organism has been a key player in many important discoveries, including breakthroughs that won Nobel Prizes. Scientists use it because its biological systems share similarities with humans, making it a useful model for studying aging and disease.

Professor Antonio Jesús Meléndez Martínez, who leads the research team, has dedicated 15 years to studying phytoene. His team focuses on finding sustainable ways to create healthier foods that can reduce the risk of disease. They are particularly interested in how carotenoids like phytoene can be applied not only in nutrition but also in agriculture and cosmetics.

One of the standout features of phytoene is how well it is absorbed by the body. Studies have shown that it collects in various tissues, including the skin, where it may even offer protection against ultraviolet (UV) radiation. This suggests that phytoene could be useful not only for extending life and fighting disease but also for protecting the skin from sun damage.

The researchers are hopeful that their findings will lead to new applications for phytoene in improving health and preventing diseases like Alzheimer’s. This discovery marks an important step in understanding how natural compounds can promote longer, healthier lives.

With more research and support, phytoene could become an important part of future health strategies aimed at fighting age-related diseases and enhancing longevity.

If you care about brain health, please read studies about vitamin D deficiency linked to Alzheimer’s and vascular dementia, and higher magnesium intake could help benefit brain health.

For more information about brain health, please see recent studies about antioxidants that could help reduce dementia risk, and coconut oil could help improve cognitive function in Alzheimer’s.

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