A new weight loss pill called amycretin has helped people lose up to 13% of their body weight in just three months, according to a recent study presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain.
The study was conducted by Novo Nordisk, a pharmaceutical company based in Denmark.
Amycretin is unique because it combines the effects of two hormones that play important roles in regulating appetite and hunger.
These hormones, amylin and glucagon-like peptide-1 (GLP-1), help control when we feel hungry and how much we eat.
While there are currently other weight loss treatments available that work on these hormones, most of them require injections. Amycretin, however, is a pill that can be taken once a day.
In this Phase I trial, which is an early stage of testing to check safety and effectiveness, participants were given different doses of amycretin to see how it affected their weight.
The trial included adults with a Body Mass Index (BMI) of 25.0 to 39.9 who did not have diabetes. They were randomly given either amycretin or a placebo (a pill with no active ingredients) once a day for 12 weeks.
The results were impressive. Participants who took the highest dose of amycretin (2 x 50 mg) lost an average of 13.1% of their body weight over the 12-week period.
Those taking a lower dose (50 mg) lost an average of 10.4% of their body weight. In comparison, participants who took the placebo only lost about 1.1% of their body weight.
Importantly, the weight loss for people taking amycretin hadn’t reached a plateau by the end of the study, suggesting that with more time, they could potentially lose even more weight.
The study also looked at the safety of amycretin. Most of the side effects were mild or moderate and were related to the digestive system, such as nausea and vomiting.
The researchers concluded that amycretin appeared to be safe and well-tolerated for people without diabetes who were overweight or obese.
The study’s authors believe that amycretin could offer a more convenient and effective option for people struggling with weight loss.
Since it targets two key biological processes in one pill, it may provide better results than current treatments. However, the researchers emphasized that more extensive studies are needed to fully understand the drug’s long-term safety and effectiveness.
Overall, this early trial of amycretin shows promising results for people looking for a new, easy-to-use option to help with weight loss.
If you care about weight loss, please read studies about the right diet for weight loss in type 2 diabetes, and is it possible to lose weight without diet and exercise.
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