Cannabis users need over 200% higher dosage of sedation in surgeries

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A recent study from Colorado has uncovered a significant finding regarding the use of cannabis and its impact on medical procedures.

Researchers discovered that patients who regularly use cannabis may require more than double the usual amount of sedation when undergoing routine medical procedures.

This could have important implications for both patients and healthcare providers.

The study, led by Mark Twardowski and published in The Journal of the American Osteopathic Association, analyzed the medical records of 250 patients who underwent endoscopic procedures after 2012, the year Colorado legalized recreational cannabis.

Endoscopic procedures, such as colonoscopies, often require sedation to ensure patient comfort and safety.

The research team found that patients who smoked or ingested cannabis on a daily or weekly basis needed significantly higher doses of sedative medications to achieve the desired level of sedation.

Specifically, these patients required 14% more fentanyl, 20% more midazolam, and a staggering 220% more propofol compared to patients who did not use cannabis regularly.

Fentanyl and midazolam are commonly used to relieve pain and anxiety during procedures, while propofol is a powerful sedative that induces and maintains anesthesia.

The need for increased sedation in cannabis users raises concerns because many sedative drugs come with dose-dependent side effects. This means that as the dosage increases, so does the risk of complications.

One of the most serious side effects associated with higher doses of sedatives is suppressed respiratory function, which can be particularly dangerous during medical procedures.

The researchers believe that cannabis may have metabolic effects that alter how the body processes certain medications, though the exact mechanisms are not yet fully understood.

They emphasize the importance of patients being aware that their cannabis use could make other medications less effective, potentially leading to complications during and after medical procedures.

Additionally, the study highlights the broader health implications of regular cannabis use. Previous research has shown that chronic cannabis use can lead to symptoms such as persistent nausea and may also require much higher dosages of anesthetics for general anesthesia.

Furthermore, cannabis users have been found to experience higher rates of post-operative seizures, adding another layer of risk.

To address these concerns, the researchers suggest that healthcare providers should start by asking specific questions about cannabis use during patient intake.

This information could be crucial in tailoring sedation plans and ensuring patient safety. Understanding a patient’s cannabis use could help doctors anticipate the need for higher doses of sedatives and monitor for potential side effects more closely.

The findings from this study are particularly relevant as cannabis use becomes more common in places where it is legalized.

As more people use cannabis recreationally or medically, it’s important for both patients and healthcare providers to understand how this might impact other aspects of medical care, especially when it comes to sedation and anesthesia.

For those interested in the broader implications of cannabis use, recent studies have linked regular cannabis use to an increased risk of heart attacks, and high-potency cannabis has been shown to potentially affect memory functions.

These findings contribute to a growing body of research that suggests while cannabis may have therapeutic benefits for some, it also carries risks that need to be carefully managed.

In conclusion, this study underscores the need for heightened awareness and caution when it comes to cannabis use and medical procedures.

By integrating questions about cannabis use into patient evaluations, healthcare providers can better prepare for potential complications and ensure safer outcomes for their patients.

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