People with essential tremor have higher dementia risk

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Research to be shared at the upcoming 76th Annual Meeting of the American Academy of Neurology reveals a concerning link between essential tremor, a common movement disorder, and an increased risk of dementia.

Essential tremor, known for causing involuntary shaking, primarily affects the arms and hands but can also impact the head, jaw, and voice. This condition is more prevalent than Parkinson’s disease, affecting millions worldwide.

The study, led by Elan D. Louis from the University of Texas Southwestern Medical Center, observed 222 individuals with essential tremor, with an average starting age of 79, over a five-year period.

Through initial and follow-up cognitive tests, researchers sought to track the progression from normal cognitive function to mild cognitive impairment and dementia among participants.

At the study’s outset, most participants exhibited normal cognitive abilities, with some already showing signs of mild cognitive impairment or dementia. Over the course of the study, 59 participants progressed to mild cognitive impairment, and 41 developed dementia.

Comparisons with the general population and those suffering from Parkinson’s disease revealed stark differences. The incidence of dementia in the essential tremor group was found to be three times higher than in the general population, although lower than in Parkinson’s patients.

Similarly, the rate of progression to mild cognitive impairment was nearly double that of the general population, indicating a significant but less severe risk than for those with Parkinson’s disease.

These findings underscore the need for increased awareness among both medical professionals and those living with essential tremor.

The association between essential tremor and a heightened risk of developing cognitive impairments, including dementia, suggests the importance of monitoring cognitive health in these patients.

Elan D. Louis emphasizes the importance of educating patients and their families about the potential cognitive risks associated with essential tremor.

Although not all individuals with this condition will face cognitive decline, understanding the increased risk can aid in planning and managing potential changes related to dementia and cognitive impairment.

The study also highlights the need for further research into the mechanisms linking essential tremor to cognitive decline, aiming to improve prevention and treatment strategies.

While essential tremor has long been associated with physical challenges, its potential impact on cognitive health opens new avenues for understanding and addressing the needs of those affected by this disorder.

This research brings to light the complex nature of essential tremor, beyond the visible symptoms of shaking, and the necessity for a comprehensive approach to care that includes both physical and cognitive health considerations.

As the medical community continues to explore the connections between movement disorders and cognitive health, studies like this one play a crucial role in enhancing our understanding and support for those affected.

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