Dementia is a modern disease, study shows

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Recent research led by the University of Southern California (USC) has offered a fascinating insight into the history of dementia, particularly in the context of ancient Greek and Roman civilizations.

Published in the Journal of Alzheimer’s Disease, this study suggests that severe memory loss, akin to what we see in Alzheimer’s and other dementias today, was exceedingly rare over 2,000 years ago.

The study delves into classical Greek and Roman medical texts, examining the writings of notable figures like Aristotle, Galen, and Pliny the Elder.

Interestingly, these ancient texts reveal very few instances that resemble even mild cognitive impairment (MCI), let alone the severe memory, speech, and reasoning loss associated with Alzheimer’s disease.

The team meticulously analyzed these ancient writings. They observed that while the Greeks acknowledged aging-related memory issues, these were not on the scale of major dementia.

Hippocrates’ texts, for instance, mention ailments like deafness and dizziness in the elderly but skip over significant memory loss.

The situation slightly shifts in ancient Rome, with a few more mentions of memory-related issues.

Galen notes learning difficulties in some elderly at the age of 80, and Pliny the Elder recounts a senator forgetting his own name. Even then, such cases seem rare and not indicative of an epidemic like we witness today.

The team proposes that the rise in cognitive decline during the Roman period could be linked to increasing urban density and resulting pollution.

The team also points to the prevalent use of lead in cooking vessels, water pipes, and even in wine as potential contributors to neurotoxicity. Some scholars have even speculated that lead poisoning played a role in the fall of the Roman Empire.

Interestingly, to understand the aging process in ancient times, the team turned to a modern-day population: the Tsimane Amerindians of the Bolivian Amazon.

The Tsimane people, living a traditional lifestyle with minimal exposure to modern environmental factors, provide a unique window into ancient aging patterns.

This research adds to the growing body of evidence that Alzheimer’s disease and related dementias may be largely diseases of modern environments and lifestyles.

Factors such as sedentary behavior and air pollution are increasingly implicated in the dramatic rise of these conditions.

The study sheds light on the history of dementia and emphasizes the impact of our contemporary lifestyle on cognitive health.

For more information about dementia, please see recent studies about brain food: nourishing your mind to outsmart dementia and results showing that re-evaluating the role of diet in dementia risk.

For more information about brain health, please see recent studies about the power of healthy fats for brain health and results showing that Mediterranean diet may preserve brain volume in older adults.

The research findings can be found in Journal of Alzheimer’s Disease.

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