A study by the University of Vermont has brought new insights into the benefits of bariatric surgery, beyond just weight loss.
Published in the American Journal of Physiology-Lung Cellular and Molecular Physiology, the research found that this surgery not only leads to significant weight loss but also improves lung function.
Additionally, it was observed that plasma taken from patients after surgery showed a reduced inflammatory response in airway-lining cells compared to before surgery.
This study adds to the existing evidence on the positive outcomes of bariatric surgery, such as weight reduction and enhanced lung function.
The researchers aimed to uncover the mechanisms behind these benefits to potentially develop new treatments for obese patients with asthma. They also explored other methods, like exercise and diet changes, that could mimic the advantages of weight loss.
The research team focused on understanding how obesity and weight loss influence the airways, particularly in relation to asthma. They studied cells that line the airways and are responsible for controlling airway constriction.
By examining the effects of circulating fat-derived factors from both asthmatic and non-asthmatic obese patients undergoing bariatric surgery, the team gathered comprehensive data.
This data included lung function, body mass index, self-reported asthma management, and fat tissue samples collected during surgery. Plasma samples were taken before and after the surgery at various stages.
Paola E. Peña García, a Ph.D. candidate and the study’s lead author, mentioned that while weight loss is undoubtedly beneficial, fat-derived factors might not be the primary influencers in obese asthma.
The team acknowledges the need for further research to completely understand the impact of obesity and weight loss on asthma treatment.
This study opens new avenues for treating asthma in obese patients, suggesting that the benefits of bariatric surgery might extend beyond weight loss to include respiratory health improvements.
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The research findings can be found in the American Journal of Physiology-Lung Cellular and Molecular Physiology.
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