Waist circumference can predict infertility in women

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A study published in PLOS ONE by Jierong Ke and colleagues from Huizhou Central People’s Hospital in China highlights the significance of waist circumference (WC) as a predictor of female infertility, independent of body mass index (BMI).

The research, which analyzed data from 3,239 female participants aged 18 to 45 years in the U.S. National Health and Nutrition Examination Survey, sheds light on the intricate relationship between abdominal obesity and fertility.

Key insights from the study include:

The study found that WC was positively associated with female infertility, regardless of BMI. For every 1cm increase in WC, the risk of infertility rose by 3 percent.

Women in the highest quintile of WC faced more than double the risk of infertility compared to those in the lowest quintile, with an odds ratio of 2.64.

There is a nonlinear yet positively dose-dependent link between WC and female infertility. This relationship varies based on the level of recreational activities engaged in by the participants.

Among those who had moderate recreational activities, an inverted U-shaped relationship was observed between WC and female infertility, with a turning point at 113.5cm. For participants with deficient recreational activities, the relationship took on a J-shaped curve, with a turning point at 103cm.

The study suggests that moderate recreational activities could mitigate the risk of infertility associated with abdominal obesity.

This research is pivotal in understanding the complex factors contributing to female infertility. It underscores the importance of considering WC as a distinct factor, separate from BMI, in evaluating fertility issues.

Furthermore, it emphasizes the potential benefits of engaging in moderate physical activities to reduce infertility risks related to abdominal obesity.

The findings have significant implications for public health and personal health management, especially for women of childbearing age.

They highlight the need for targeted lifestyle interventions focusing on managing WC to improve fertility outcomes.

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The research findings can be found in PLOS ONE.

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