For people with Type 2 diabetes, managing blood sugar levels can be a real challenge.
Most start with a drug called metformin, but over time, it might stop working well enough. This is where a recent study from Thomas Jefferson University comes in, offering some hopeful news.
This study focused on a mix of two diabetes drugs: dapagliflozin and exenatide. Researchers wanted to see if this combination could help people whose diabetes wasn’t under control with just metformin.
Here’s what they did: they took 695 adults with Type 2 diabetes and divided them into three groups. One group got weekly shots of exenatide plus metformin.
Another took daily dapagliflozin pills with metformin, and the third group got both drugs. This study was a follow-up to an earlier trial, giving patients the chance to stay in the study for two years.
The cool thing about these two drugs is how they work together. Dapagliflozin gets rid of excess sugar through urine, while exenatide helps the body secrete insulin when needed, lowers sugar production in the liver, slows down food leaving the stomach, and makes people feel fuller.
When used together, these drugs not only control blood sugar better but also help in losing weight and lowering blood pressure.
And guess what? The study found that patients who took both drugs had better blood sugar control than those who took just one. Even better, this effect lasted for the whole two years of the study.
Patients also lost weight and saw their blood pressure go down. These are important because they can both affect Type 2 diabetes and overall health.
There were no big safety issues with using both drugs together. Other studies have shown that using these drugs can also improve things like cholesterol levels.
The researchers pointed out that many diabetes treatments don’t work as well over time. That’s why it’s so exciting to see that this drug combo kept working for over two years. It’s a big deal for people struggling to control their diabetes.
This research, led by Serge Jabbour and published in the journal Diabetes Care, offers a ray of hope. It shows that the combination of dapagliflozin and exenatide could be a powerful tool in managing Type 2 diabetes effectively over the long haul.
If you care about blood sugar, please read studies about why blood sugar is high in the morning, and how to cook sweet potatoes without increasing blood sugar.
For more information about brain health, please see recent studies about 9 unhealthy habits that damage your brain, and results showing this stuff in cannabis may protect aging brain, treat Alzheimer’s.
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