Heart failure may not be a death risk for people with cancer

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Cancer patients receiving anthracycline chemotherapy face a significant risk of developing heart failure. The RESILIENCE project, an international effort funded by the EU, aims to prevent heart failure in these patients.

Experts and patients gathered to discuss strategies to enhance cancer patients’ healthcare and quality of life.

Anthracycline chemotherapy is essential for treating various cancers, including lymphoma. However, it carries the risk of heart problems. Currently, there are no therapies to prevent anthracycline-induced heart issues.

The RESILIENCE project is testing a preventive treatment called remote ischaemic conditioning in lymphoma patients at risk for heart problems due to anthracycline chemotherapy.

The trial involves over 600 non-Hodgkin lymphoma patients from seven EU countries, with some already enrolled.

Patients are randomly assigned to receive either remote ischaemic conditioning or a sham intervention once a week at home during four months of chemotherapy. Remote ischaemic conditioning involves temporarily stopping blood supply to one arm to protect organs from injury.

The project brings together cardiologists, oncologists, patients, and other stakeholders to reduce heart damage caused by cancer treatment.

Patient perspectives play a crucial role in designing the study, and their experiences will be collected during the trial.

The RESILIENCE project collaborates with the European Society of Cardiology (ESC) and aligns with the ESC’s guidelines on cardio-oncology.

The ESC helps disseminate the study results and educates healthcare professionals on minimizing cardiac side effects of cancer treatment.

The ultimate goal of the RESILIENCE project is to improve the quality of life for cancer patients by reducing the risk of heart failure during and after anthracycline chemotherapy.

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