New Generation Blood Thinners Show Promise
In a groundbreaking study from the University of Gothenburg, modern blood-thinning drugs, commonly referred to as NOACs (non-vitamin K oral anticoagulants), have shown to reduce the risk of severe bleeding by up to 45% compared to the traditional drug warfarin, also known under the brand name Waran.
A New Paradigm in Blood Thinning Medication
For over fifty years, warfarin has been a standard treatment for preventing blood clots. However, NOACs have been gradually taking over, thanks to previous studies showing their efficacy in short-term treatments.
Now, this comprehensive study confirms the benefits of NOACs, particularly apixaban, which is sold under the brand name Eliquis, in both short-term and extended treatments for blood clots in legs and lungs.
The Swedish Study
The study is based on a registry that includes 45,000 patients treated for blood clots between 2014 and 2020. The research shows a clear advantage for NOACs, specifically apixaban.
Katarina Glise Sandblad, the study’s lead author, says, “We see that apixaban is associated with a lower risk of bleeding in both the short and the long term compared to warfarin.
The short-term risk of bleeding is also lower compared to rivaroxaban (Xarelto).”
Waran Still Has a Role to Play
While the prescription rate for warfarin is on a decline, it still remains relevant in certain situations.
Sandblad emphasizes, “Today, if a patient is prescribed Waran for the first time, it is generally for a good reason.”
Patients with specific conditions such as atrial fibrillation, mechanical heart valves, or blood coagulation disorders may still require warfarin. However, for the vast majority, switching to a NOAC could be more beneficial.
Conclusion
The study establishes apixaban as an effective and safer alternative to warfarin in treating blood clots in the legs and lungs.
These findings could have a significant impact on the choices doctors make when prescribing blood thinners and open new doors for safer, more effective treatments for patients worldwide.
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