Obesity is a major global health concern, significantly contributing to the risk of lifestyle diseases such as diabetes and hypertension.
Addressing this issue, a multi-institutional research group led by Associate Professor Akiko Kojima at Osaka Metropolitan University’s Graduate School of Human Life and Ecology has made a breakthrough.
Investigating the Antiobesity Effects of Mallotus Furetianus Extract
The research team previously studied the effects of the extract of Mallotus furetianus (MFE), a tropical plant native to Hainan Island, China, on preventing fatty liver disease.
However, the antiobesity effects and mechanisms of MFE remained unclear. Their recent findings, published in Food Science & Nutrition, shed light on this issue.
The researchers used obesity mouse models to investigate the antiobesity effects of MFE extract.
They found that MFE treatment significantly reduced both body and adipose tissue weight in the mice and triggered morphological changes in the liver and adipose tissue.
Revealing the Mechanism
Further investigation into the mechanism behind these effects revealed that MFE inhibits fat synthesis by suppressing the expression of various transcription factors involved in adipocyte differentiation.
The research team aims to identify food ingredients with antiobesity effects in the hope that incorporating these into daily diets can contribute to people’s health and longevity.
“These results not only suggest a link between Mallotus furetianus extract and antiobesity effects but also indicate its potential as a new food ingredient with antiobesity properties,” said Professor Kojima.
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The study was published in Food Science & Nutrition.
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