New test can predict diabetes remission after weight-loss surgery

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Diabetes is a widespread illness that impacts millions worldwide. It’s often linked to weight issues. Many who suffer from severe obesity opt for a special kind of weight-loss surgery called gastric bypass.

This surgery not only helps people shed significant weight but also often leads to the end of type 2 diabetes symptoms.

However, it’s been a puzzle for doctors: why do some patients see their diabetes vanish, while others don’t?

Researchers from the University of Utah Health believe they’ve found an answer. Let’s delve into this fascinating discovery and what it means for patients.

The Magic Substance: Ceramides

Imagine a substance in your blood that can tell doctors a lot about your health. This is what ceramides are. These tiny, waxy bits, similar to cholesterol, are found in our blood.

High levels of ceramides have been linked to diabetes. Now, for the first time, researchers have found that they can also predict how a patient’s diabetes will behave after weight-loss surgery.

In simpler terms: If you have low ceramides before surgery, there’s a high chance your diabetes will go away for a while. If they’re high, even if you lose a lot of weight, your diabetes might stick around.

What The Study Showed

To understand ceramides better, scientists did a big study. They checked the blood of over a thousand people, some who had the surgery and others who didn’t.

They found that 73% of those who had low ceramides saw their diabetes fade away after the surgery. Those with high ceramides weren’t as lucky, even if they lost a lot of weight.

What’s even more interesting is that this test can also hint at who might see their diabetes return within ten years, even after it initially went away.

But why does this matter?

Well, knowing in advance can help doctors plan better. They can provide different advice and care based on these ceramide levels.

This is a big step toward “personalized medicine” – where doctors can offer treatments and advice tailor-made for each patient.

The Bigger Picture: Gastric Bypass and Diabetes

Gastric bypass is no small thing. In this surgery, doctors make a small pouch from the stomach and connect it to the small intestine. This means patients eat less and feel full faster.

It’s a popular choice for those with severe weight problems. In the US alone, about 250,000 people get this surgery every year.

While many know about the weight loss benefits, what’s less known is its effect on diabetes. Some patients see their diabetes vanish after the surgery, at least for a while.

It’s almost like a two-in-one benefit. But until now, doctors couldn’t predict who would get this extra bonus.

Wrapping Up

The discovery of ceramides and their role is exciting. But remember, this is just the beginning. More studies are needed to fully understand these little waxy bits in our blood.

What’s promising, though, is the hope this brings. Dr. Scott Summers, one of the lead researchers, has a burning question:

Why do some people have high ceramides, and how does this lead to diabetes? Finding that out could be a big win in the fight against diabetes.

In the meantime, if you or someone you know is considering gastric bypass surgery, it might be worth discussing ceramides with the doctor.

They could provide a glimpse into the future, helping patients and doctors alike make informed choices.

If you care about diabetes, please read studies about high blood pressure drug may protect kidneys from damage in diabetes and changing breakfast habits could improve type 2 diabetes management.

For more information about diabetes, please see recent studies that blueberries strongly benefit people with metabolic syndrome, and results showing common diabetes drugs that can spike heart attack risk.

The study was published in Med.

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