Unraveling the mystery of dementia risk scores: are they accurate?

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Dementia is a term that describes a group of symptoms related to memory loss and other cognitive issues that interfere with daily life.

It is not a specific disease but a general term for the impaired ability to remember, think, or make decisions that interfere with everyday activities.

It’s like having trouble remembering the way home from your school or finding it hard to recall the names of your classmates.

Sounds scary, right? But remember, not everyone will experience dementia. Scientists and doctors are always studying ways to predict who might get dementia and how to prevent it.

The Study on Dementia Risk Scores

Now, let’s talk about a study that some scientists did recently. These scientists were led by a person named Mika Kivimäki, who works at University College London.

They wanted to see if four commonly used tests, known as ‘dementia risk scores’, were good at predicting who might develop dementia within the next ten years.

In simple terms, a ‘risk score’ is like a test that helps doctors guess whether a person might develop a certain disease in the future.

These scientists looked at a large group of people from the UK Biobank who didn’t have dementia when the study started between 2006 and 2010.

They also checked their findings in a smaller group of people from another study called the Whitehall II study.

The Findings: Not So Accurate

What they found was a bit disappointing.

When they set the tests to only have a 5% chance of wrongly predicting that someone would get dementia (this is called a ‘false positive’), these risk scores only correctly identified between 9 and 16 out of every 100 people who actually developed dementia.

That means the tests missed a lot of people – between 84 and 91 out of every 100!

Even when they just used a person’s age to guess if they might get dementia, the test still missed 84 out of 100 people.

When Trying to Catch More Cases

The scientists then tried a different approach. They set the tests to catch at least half of the people who would develop dementia.

But this meant that the tests had a lot of ‘false positives’ – they were saying people would get dementia when they actually didn’t. The tests were still not very good at picking the right people.

Comparing Different Risk Scores

When they compared the different risk scores, the one that just used a person’s age was the most accurate.

The other scores, like the one that uses information about heart health and aging (CAIDE), the Australian National University Alzheimer Disease Risk Index (ANU-ADRI), and the Brief Dementia Screening Indicator were not as good.

So, What Does This Mean?

The scientists concluded that these dementia risk scores were not very good at picking out people who might develop dementia.

This means that they might not be very useful in helping to prevent dementia, which is a bit of a letdown.

The Importance of Continued Research

But don’t worry, this doesn’t mean that we can’t do anything about dementia. It just means that scientists and doctors need to keep researching and find better ways to predict and prevent this disease.

Research is like trying to solve a big puzzle – sometimes you find a piece that fits, and sometimes you don’t.

But each piece, whether it fits or not, brings us closer to the full picture. This study is just one piece of the big puzzle that is dementia.

So, remember, while this news might sound a bit scary, there’s always hope.

With more research and effort, we can better understand diseases like dementia, how to predict them, and, hopefully, how to prevent them in the future.

If you care about dementia, please read studies about heartburn drugs that could increase risk of dementia, and this supplement could keep dementia at bay.

For more information about brain health, please see recent studies about how high blood pressure could increase your dementia risk, and results showing these antioxidants could help reduce the risk of dementia.

The study was published in JAMA Network Open.

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