More than half of patients with diabetes (51%) experienced diabetes remission after metabolic surgery, regardless of whether they achieved significant weight loss, according to a new study presented at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2023 Annual Scientific Meeting.
The research team, which included scientists from the Mayo Clinic in Rochester, the University of California San Francisco in Fresno, and the Stony Brook University Medical Center in New York, carried out a retrospective study of patients with diabetes who had undergone gastric bypass surgery between 2008 and 2017.
The study followed 815 patients with an average BMI of 45.1 for an average of seven years, making it the longest study of patients with diabetes after gastric bypass.
The researchers concluded that patients were more likely to achieve full diabetes remission if they were not using insulin before surgery, required fewer diabetes medications, had a shorter duration of the disease, lower HbA1c at baseline, and experienced higher weight loss after surgery.
Diabetes remission rates were proportional to weight loss following surgery.
Reevaluating the Role of Metabolic Surgery
“This study shows that diabetes remission is not fully contingent on weight loss after gastric bypass surgery,” said Dr. Omar Ghanem, lead study author and metabolic surgeon at Mayo Clinic in Rochester.
He emphasizes the need for close monitoring and efficient management of diabetes after surgery and argues that while metabolic surgery isn’t a magic pill, it offers many patients the best chance to rid themselves of diabetes and its complications permanently.
Dr. Teresa LaMasters, the president of ASMBS and not involved in the study, agreed with Ghanem’s sentiments and added that health professionals should consider these remission factors when selecting patients for metabolic surgery and counseling them about potential health outcomes.
“Gastric bypass has been known to put diabetes into remission even before significant weight is lost,” she said, highlighting the importance of considering such procedures in the treatment plan for diabetes patients.
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