A recent study conducted at McGill University has raised concerns about the use of anti-inflammatory drugs and steroids as pain relievers, suggesting that they may increase the likelihood of developing chronic pain.
This research challenges the long-standing practice of using anti-inflammatory drugs to alleviate pain, highlighting the potential for unintended consequences.
Unveiling the Mechanisms
The study explored the mechanisms of pain in both humans and mice, shedding light on the role of neutrophils, a type of white blood cell that aids the body in fighting infection, in resolving pain.
The researchers found that blocking neutrophils in mice prolonged the pain up to ten times longer than normal.
Surprisingly, treating pain with anti-inflammatory drugs and steroids, such as dexamethasone and diclofenac, yielded similar outcomes despite their initial effectiveness.
Supporting Evidence
The study’s findings are reinforced by a separate analysis of 500,000 individuals in the United Kingdom.
This analysis revealed that individuals who used anti-inflammatory drugs to manage pain were more likely to experience pain two to ten years later, whereas this effect was not observed in those taking acetaminophen or antidepressants.
Reconsidering Pain Management
The research suggests a need to reevaluate the approach to acute pain treatment.
While pain relief is essential, interfering with the natural inflammation response may have unintended consequences.
The study authors recommend conducting clinical trials that directly compare anti-inflammatory drugs to alternative painkillers that relieve discomfort without disrupting inflammation.
The aim is to identify new, more effective pain treatments without the associated negative side effects of anti-inflammatory drugs and steroids.
Managing Chronic Pain
Effectively managing chronic pain requires a comprehensive approach. Consider the following strategies:
Medications: Pain relievers, such as acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), opioids, and antidepressants, can provide relief. However, it is crucial to use these medications under the guidance of a healthcare professional.
Physical therapy: Engaging in physical therapy can enhance strength, flexibility, and range of motion, alleviating chronic pain. Physical therapists can also teach exercises tailored to individual needs.
Acupuncture: Traditional Chinese medicine technique of acupuncture, involving the insertion of thin needles at specific points in the body, has shown promise in pain management.
Mind-body techniques: Practicing mind-body techniques like meditation, yoga, and deep breathing can reduce stress and anxiety, which can exacerbate chronic pain.
TENS therapy: Transcutaneous electrical nerve stimulation (TENS) therapy utilizes a small device to deliver electrical impulses that help alleviate pain by targeting nerves.
Heat and cold therapy: Applying heat or cold to the affected area can provide pain relief. Heat relaxes muscles, while cold reduces inflammation.
It is crucial to collaborate with a healthcare professional to develop an individualized treatment plan for managing chronic pain effectively.
The study was published in Science Translational Medicine and led by Jeffrey Mogil et al.
If you care about chronic pain, please read studies that drinking electrolytes, not water, may help reduce muscle pain, and this pain reliever may increase your risk of hip fracture.
For more information about wellness, please see recent studies that Krill oil could improve muscle health in older people, and eating yogurt linked to lower frailty in older people.
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