Choline is a crucial nutrient that is synthesized in small amounts by the liver and can be found in various foods such as eggs, broccoli, beans, meat, and poultry.
A recent study by scientists at Arizona State University has examined the negative effects of a deficiency in dietary choline and its potential link to Alzheimer’s disease.
The study suggests that inadequate choline intake can have detrimental effects on multiple organs, including the heart and liver.
It also revealed that a lack of choline can result in big changes in the brain, such as the development of amyloid plaques and tau tangles, which are commonly observed in Alzheimer’s disease.
Using normal mice and choline-deficient transgenic mice (which already display symptoms related to Alzheimer’s disease), the team found that choline deficiency resulted in liver damage, heart enlargement, and neurologic changes in the AD mice.
Additionally, the study discovered that choline deficiency in mice led to significant weight gain, alterations in blood sugar, and deficits in motor skills.
The research also showed that humans often fail to consume the recommended daily intake of choline, which was established by the Institute of Medicine in 1998.
Furthermore, many studies suggest that the established daily intake amounts are not optimal for brain-related functions.
The study emphasizes the importance of adequate choline intake to prevent physical and neurological changes associated with choline deficiency.
Individuals on plant-based diets, which may be low in naturally occurring choline, should consider consuming choline-rich plant-based foods such as soybeans, Brussels sprouts, and certain nuts.
Moreover, over-the-counter choline supplements can be an inexpensive and effective way to promote overall health and protect the brain against neurodegeneration.
Overall, the study by Ramon Velazquez et al, published in Aging Cell, highlights the need to increase awareness of choline’s importance in maintaining human health and the potential link between choline deficiency and Alzheimer’s disease.
If you care about Alzheimer’s, please read studies that herpes virus is a cause of Alzheimer’s disease, and this plant compound may help treat Alzheimer’s.
For more information about brain health, please see recent studies about possible way to delay or reverse Alzheimer’s disease, and results showing blueberry supplements may prevent cognitive decline.
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