Scientists find new drug against weight gain even on a high-fat, high-sugar diet

Credit: Valeria Boltneva / Pexels

Scientists from The University of Texas Health Science Center at San Antonio have discovered a new drug that could help people lose weight and prevent liver problems caused by a diet high in sugar and fat.

To understand how the drug works, we need to know a bit about how our bodies process energy.

Our cells have little power plants called mitochondria that produce energy from the food we eat.

One nutrient that’s important for healthy mitochondria is magnesium, which helps regulate blood sugar, blood pressure, and bone health.

But the researchers found that too much magnesium can slow down energy production in the mitochondria.

To test this idea, they removed a gene that helps transport magnesium into the mitochondria in mice.

These mice were able to burn sugar and fat more efficiently, and as a result, they stayed skinny and healthy even when fed a high-sugar, high-fat diet.

The researchers then created a drug called CPACC that mimics the effect of removing the magnesium gene.

When they gave this drug to mice, the mice were able to lose weight and avoid the liver problems that often come with a high-sugar, high-fat diet.

The drug is exciting because it could potentially help people avoid health problems caused by a poor diet, like obesity, type 2 diabetes, and heart disease.

The researchers are continuing to work on developing the drug, and they’ve already filed a patent application for it.

Overall, this discovery is important because it shows that understanding how our bodies process energy can help us develop new treatments for health problems caused by a poor diet.

Obesity is a medical condition where a person’s body has an excess amount of body fat that can negatively impact their health.

It is typically diagnosed using a person’s body mass index (BMI), which takes into account their height and weight. If a person’s BMI is 30 or higher, they are considered to be obese.

Obesity can increase the risk of developing a range of health problems, including type 2 diabetes, heart disease, high blood pressure, sleep apnea, and certain cancers.

It can also lead to a lower quality of life, as people with obesity may experience discrimination and face challenges with daily activities.

Obesity is caused by a combination of factors, including genetics, lifestyle, and environmental factors. Eating a diet high in calories and fat, as well as not getting enough physical activity, can contribute to obesity.

Certain medical conditions and medications can also increase the risk of developing obesity.

Treating obesity typically involves lifestyle changes like eating a healthy diet and increasing physical activity.

In some cases, medication or weight loss surgery may also be recommended. It’s important to talk to a healthcare provider about the best course of treatment for individual cases of obesityTop of FormBottom of Form

A high-fat diet is a type of diet where a person consumes a high amount of fat, often at the expense of other nutrients like carbohydrates and protein.

In general, a high-fat diet is defined as a diet where more than 30% of the calories come from fat.

High-fat diets can vary in the types of fat consumed, with some people consuming more saturated fats (found in foods like red meat and dairy products) while others consume more unsaturated fats (found in foods like nuts, seeds, and fatty fish).

While fat is an important nutrient that our bodies need to function properly, consuming too much fat can lead to health problems.

A diet high in saturated and trans fats can increase the risk of heart disease, as it can raise levels of LDL (or “bad”) cholesterol in the blood.

Consuming too many calories overall, including fat, can also lead to weight gain and obesity.

If you care about health, please read studies about new drugs to treat diabetes and metabolic syndrome, and heavy cannabis use may decrease the incidence of diabetes.

For more information about weight loss, please see recent studies that Mediterranean diet can reduce belly fat much better, and Keto diet could help control body weight and blood sugar in diabetes.

The study was conducted by Travis R. Madaris et al and published in Cell Reports.

Copyright © 2023 Knowridge Science Report. All rights reserved.