People with ‘healthy obesity’ have higher risk of chronic kidney disease

Credit: Robina Weermeijer / Unsplash

In a study from Koc University, scientists found metabolically healthy overweight and obese individuals may have an increased risk for chronic kidney disease (CKD).

CKD is a longstanding disease of the kidneys leading to renal failure.

The disease involves a gradual loss of kidney function. Your kidneys filter wastes and excess fluids from your blood, which are then removed in your urine.

Advanced chronic kidney disease can cause dangerous levels of fluid, electrolytes and wastes to build up in your body.

Symptoms develop slowly and aren’t specific to the disease. Some people have no symptoms at all and are diagnosed by a lab test.

Medication helps manage symptoms. In later stages, filtering the blood with a machine (dialysis) or a transplant may be required.

In the study, the researchers conducted a systematic review and meta-analysis to examine the associations between obesity and CKD independent of metabolic syndrome by focusing on metabolically healthy obese people.

Data were included from 16 studies, with 4,965,285 participants.

The researchers found that the risk for CKD was higher in overweight and obese patients compared with healthy normal-weight participants.

The prevalence of metabolically healthy obesity is about 35% in obese people. Treating this condition could have important public health implications.

Future work needs to examine whether lifestyle and medical treatment may prevent CKD and heart disease in the metabolically healthy overweight and obese population.

If you care about weight loss, please read studies that hop extract could reduce belly fat in overweight people, and early time-restricted eating could help lose weight.

For more information about kidney health, please see recent studies about foods that may prevent recurrence of kidney stones, and eating nuts linked to lower risk of chronic kidney disease and death.

The study was conducted by Mehmet Kanbay et al and published in the European Journal of Clinical Investigation.

Copyright © 2023 Knowridge Science Report. All rights reserved.