In a study from the Cancer Registry of Norway, scientists found lifestyle habit changes are associated with colorectal cancer (CRC) risk.
They examined changes in lifestyle habits and their associations with colon cancer development using data from the European Prospective Investigation into Cancer cohort.
A healthy lifestyle index (HLI) score was developed based on smoking status, alcohol consumption, body mass index, and physical activity.
The researchers found 2,799 colon cancer cases among 295,865 participants during a follow-up of 7.8 years.
They found each unit increase in the healthy lifestyle index was linked to a strong 3% reduction in colon cancer risk.
For patients in the top tertile at baseline, the risk for colon cancer was higher for those in the bottom tertile at follow-up versus those remaining in the top tertile.
For those in the bottom tertile at baseline, colon cancer risk was lower for those in the top tertile at follow-up compared with those remaining in the bottom tertile.
Based on the findings, the team suggests that changes in lifestyle habits in adult life are linked to the risk of colon cancer.
Favorable changes were linked to a reduced risk of colon cancer risk, whereas unfavorable changes were associated with an increased risk of colon cancer.
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The study was conducted by Edoardo Botteri et al and published in The American Journal of Gastroenterology.
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