Research shows the possible cause of Alzheimer’s disease

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In a recent study from Curtin University, scientists found a likely cause of Alzheimer’s disease.

They found that a probable cause of Alzheimer’s disease was the leakage from the blood into the brain of fat-carrying particles transporting toxic proteins.

The researchers say the probable ‘blood-to-brain pathway’ that may lead to Alzheimer’s disease, the most prevalent form of dementia globally.

This ‘blood-to-brain pathway’ is important because if doctors can manage the levels in the blood of lipoprotein-amyloid and prevent their leakage into the brain, this opens up potential new treatments to prevent Alzheimer’s disease and slow memory loss.

In the study, researchers tested the ground-breaking ‘blood-to-brain pathway’ by genetically engineering mouse models to produce a human amyloid-only liver that makes lipoproteins.

They found that mouse models producing lipoprotein-amyloid in the liver suffered inflammation in the brain, accelerated brain cell death, and memory loss.

This finding shows the abundance of these toxic protein deposits in the blood could potentially be addressed through a person’s diet and some drugs that could specifically target lipoprotein amyloid, therefore reducing their risk or slowing the progression of Alzheimer’s disease.

The findings may have a significant global impact on the millions of people living with Alzheimer’s disease.

If you care about brain health, please read studies about cause of Alzheimer’s disease, and personality that may protect you from Alzheimer’s disease.

For more information about brain health, please see recent studies about how to eat your way to a healthy brain, and how to prevent brain aging effectively.

The study was published in PLOS Biology and conducted John Mamo et al.

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