Artificial sweeteners reduce added sugar content and corresponding calories while maintaining sweetness.
A new study from French National Institute for Health and Medical Research found that some artificial sweeteners are associated with increased cancer risk.
The study is published in PLOS Medicine and was conducted by Charlotte Debras et al.
Many food products and beverages containing artificial sweeteners are consumed by millions of people daily. However, the safety of these additives has been a subject of debate.
In the study, the team analyzed data from 102,865 French adults participating in the NutriNet-Santé study.
Researchers gathered data concerning artificial sweetener intake from 24-hour dietary records.
They found that people consuming larger quantities of artificial sweeteners, particularly aspartame and acesulfame-K, had a higher risk of overall cancer compared to non-consumers.
Higher risks were observed for breast cancer and obesity-related cancers.
The findings do not support the use of artificial sweeteners as safe alternatives for sugar in foods or beverages and provide important information to address the controversies about their potential adverse health effects.
They provide important and novel insights for the ongoing re-evaluation of food additive sweeteners.
Recent studies have found these snacks may increase your death risk in heart disease and cancer, and new cancer drug is more effective with fewer side effects, which are highly relevant to the current study.
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While sugar has a strong connection with cancer risk, some studies have found that certain types of sugar can slow down cancer growth.
A recent study from the Cancer Research UK Beatson Institute and published in Nature found that Mannose sugar could slow tumor growth and improve the effects of chemotherapy with multiple types of cancer.
The study is one step towards understanding how mannose could be used to help treat cancer.
Previous research has shown that tumors use more glucose than normal, healthy tissues. But it is very hard to control the amount of glucose in your body through diet alone.
In the study, the team found that mannose could interfere with glucose to reduce how much sugar cancer cells can use.
Because tumors need a lot of glucose to grow, limiting the amount they can use should slow cancer progression.
But the problem is that normal tissues need glucose as well, so scientists can’t completely remove it from the body.
Luckily, the researchers found a dosage of mannose that could block enough glucose to slow tumor growth, but not so much that normal tissues were affected.
They examined how mice with pancreatic, lung or skin cancer responded when mannose was added to their drinking water and given as an oral treatment.
The results showed that the supplement strongly slowed down the growth of tumors and did not cause any obvious side effects.
The team also found mannose could affect cancer treatment, including cisplatin and doxorubicin, two of the most widely used chemotherapy drugs.
They found that mannose enhanced the effects of chemotherapy, slowing tumor growth, reducing the size of tumors and even increasing the lifespan in mice.
Several other cancer types, including leukemia, osteosarcoma, ovarian and bowel cancer, were also examined.
The team’s next step is checking why treatment only works in some cells so that they can work out which patients might benefit the most from this approach.
If you care about cancer, please read studies about a new method to treat cancer effectively, and this low-dose, four-drug combo may block cancer spread.
For more information about cancer prevention, please see recent studies about nutrient in fish that can be a poison for cancer, and results showing this daily vitamin is critical to cancer prevention.
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