In a new study from the Los Angeles County Department of Public Health, researchers found COVID-19 risk and hospitalization are consistently higher for unvaccinated people, and rates are lowest for those fully vaccinated with a booster.
They examined the 14-day COVID-19 incidence and hospitalization rates from Nov. 7, 2021, to Jan. 8, 2022.
The researchers found that the incidence and hospitalization rates, respectively, among unvaccinated people, were 12.3 and 83.0 times those of fully vaccinated people with a booster and 3.8 and 12.9 times those of fully vaccinated persons without a booster.
The 14-day period ended Dec. 11, 2021, which was the last week of delta predominance.
During omicron predominance (week ending Jan. 8, 2022), these rate ratios were lower, with unvaccinated people having an infection and hospitalization rates, respectively, 3.6 and 23.0 times those of fully vaccinated people with a booster and 2.0 and 5.3 times those of fully vaccinated people without a booster.
Admission to intensive care units, intubation for mechanical ventilation, and death were much more likely among unvaccinated persons than among fully vaccinated persons with or without a booster during the entire analytic period.
The team says efforts to promote COVID-19 vaccination and boosters are critical to preventing COVID-19-associated hospitalizations and severe outcomes.
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The study is published in Morbidity and Mortality Weekly Report and was conducted by Phoebe Danza et al.
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