In a new study from Weill Cornell Medicine-Qatar, researchers found previous COVID-19 infection is about 90 percent effective for preventing reinfection with the alpha, beta, and delta variants but offers lower protection against reinfection with the Omicron variant.
In the study, the team extracted data related to COVID-19 vaccination and clinical infections.
They found that the effectiveness of the previous infection in preventing reinfection was estimated to be 90.2, 85.7, 92.0, and 56.0 percent against the Alpha, Beta, Delta, and Omicron variants, respectively.
The study results were confirmed in sensitivity analyses.
Among patients with reinfection, progression to severe COVID-19 occurred in one, two, none, and two patients with the Alpha, Beta, Delta, and Omicron variants, respectively.
Reinfections did not progress to critical or fatal diseases. With respect to protection against severe, critical, or fatal COVID-19, the effectiveness of the previous infection was 69.4, 88.0, 100, and 78.8 percent against the alpha, beta, delta, and Omicron variants, respectively.
The team says the protection of the previous infection against hospitalization or death caused by reinfection appeared to be robust, regardless of variant.
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The study is published in the New England Journal of Medicine and was conducted by Heba N. Altarawneh et al.
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