Many people have long-term attention and memory deficits after mild COVID

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In a new study from Oxford, researchers found that people who have had COVID but don’t complain of long COVID symptoms in daily life nevertheless can show degraded attention and memory for up to 6–9 months.

Previous studies have shown that after acute COVID-19 infection some people can continue to suffer from cognitive symptoms such as difficulties in concentrating, colloquially referred to as brain fog, as well as forgetfulness and fatigue—features of the ‘long COVID’ syndrome.

But it was not known whether cognitive performance can also be affected in individuals who had mild symptoms and reported no concerns after recovery from acute COVID infection.

In this study, participants were asked to complete a number of exercises to test their memory and cognitive ability, with a focus on cognitive functions critical for daily life, such as sustaining attention, memory, planning and semantic reasoning.

All the participants had previously suffered from COVID-19 but were not significantly different from a control group at the time of testing on factors such as fatigue, forgetfulness, sleep patterns or anxiety.

The team found that the participants performed well in most abilities tested, including working memory and planning, but they displayed much worse episodic memory (up to six months post-COVID infection) and a greater decline in the ability to sustain attention over time (for up to nine months) than uninfected individuals.

What is surprising is that although the COVID-19 survivors did not feel any more symptomatic at the time of testing, they showed degraded attention and memory.

The findings reveal that people can experience some chronic cognitive consequences for months.

Researchers still do not understand the mechanisms that cause these cognitive deficits, but it is very encouraging to see that this attention and memory return largely to normal in most people we tested by 6-9 months after infection, who demonstrated good recovery over time.

If you care about Covid, please read studies about people who are more likely to get severe COVID-19 after vaccination, and drug combo that could effectively fight COVID-19.

For more information about brain health, please see recent studies about common liver drug that may treat dementia effectively, and results showing that healthy lifestyle can reduce dementia even if you have a family history of the disease.

The study is published in Brain Communications. One author of the study is Dr. Sijia Zhao.

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