In a new study from the University of Kentucky, researchers found new evidence that resistance exercise has unique benefits for fat loss.
They found that resistance-like exercise regulates fat cell metabolism at a molecular level.
The study results in mice and humans show that in response to mechanical loading, muscle cells release particles called extracellular vesicles that give fat cells instructions to enter fat-burning mode.
Extracellular vesicles were initially understood as a way for cells to selectively eliminate proteins, lipids and RNA.
Recently, scientists discovered that they also play a role in intercellular communication.
The study adds a new dimension to how skeletal muscle communicates with other tissues by using extracellular vesicles.
The team says this is the first demonstration of how weight training initiates metabolic adaptations in fat tissue, which is crucial for determining whole-body metabolic outcomes.
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The study is published in the FASEB Journal. One author of the study is John McCarthy, Ph.D.
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