Scientists find new way to reduce obesity

Credit: CC0 Public Domain

In a new study, researchers have found a new method of reducing human body weight and fat mass using weighted vests.

The new study indicates that there is something comparable to built-in bathroom scales that contributes to keeping our body weight and, by the same token, fat mass constant.

The research was conducted by scientists from the University of Gothenburg, Sweden.

The researchers hypothesized that loading the vests with weights would result in a compensatory body-weight decrease.

Sixty-nine people with a body mass index (BMI) of 30-35, the lowest obesity category, took part in the clinical study.

Their instructions were to wear a weighted vest eight hours a day for three weeks, and otherwise live as usual.

All the study participants wore weighted vests but, by drawing of lots, they were assigned to one of two groups.

The control group wore only light vests weighing 1 kg, while the treatment group wore heavy vests weighing some 11 kg.

When the three weeks had passed, the experimental subjects who wore the heavier vests had lost 1.6 kg in weight, while those wearing the light vests had lost 0.3 kg.

The team says it’s very interesting that the treatment with the heavier weighted vests reduced fat mass while muscle mass simultaneously remained intact.

The effect on fat mass they found, from this short experiment, exceeded what’s usually observed after various forms of physical training.

But the researchers weren’t able to determine whether the reduction was in subcutaneous fat (just under the skin) or the dangerous visceral kind (belly fat) in the abdominal cavity that’s most strongly linked to heart diseases and diabetes.

In previous studies, the scientists showed that there is an energy balance system that endeavors to keep body weight constant: the “gravitostat,” as they have dubbed it.

In mice, this regulation takes place partly by influencing appetite. To work, the system must contain a kind of personal weighing machine.

The researchers’ new clinical study shows that similar built-in scales exist in humans as well.

If people do a lot of sitting, what seems to happen is that the reading on our personal scales falls too low.

This may explain why sitting is so clearly associated with obesity and ill-health. Weighted vests can raise the reading on the scales, resulting in weight loss.

Many questions about how the gravitostat works remain for the researchers to answer.

Aspects they want to study include whether, in wearers of weighted vests, changed energy expenditure, appetite and mobility help them to lose weight.

The scientists also want to see whether the weight reduction continues for the vest wearers over periods longer than three weeks and whether the dangerous visceral fat is reduced by the treatment.

The lead author of the study is Professor Claes Ohlsson from Sahlgrenska Academy, University of Gothenburg.

The study is published in EClinicalMedicine.

Copyright © 2020 Knowridge Science Report. All rights reserved.