In a new study, researchers found that vegetable hormones may help reverse brain changes caused by obesity and type 2 diabetes, high-fat diets and lack of physical activity.
The research was conducted by a team from Universitat Jaume I (UJI) in Castellón, Spain.
Previous research has shown that high-fat and sugary diets, combined with a lack of physical exercise, can cause metabolic syndrome and inflammation in the brain.
This can cause degenerative processes and eventually lead to diseases such as Alzheimer’s disease.
In the study, the team examined how a vegetable hormone, abscisic acid, is able to counter the harmful effects of high-fat diets on the brain.
The team found that the expression of proteins required for the proper functioning of insulin decreased in neuroinflammation caused by a high-fat diet.
But when more abscisic acid was added to the high-fat diet, it could reverse the change to normal levels.
The team suggests that the finding may help develop a vegetable hormone treatment for obesity and diabetes.
It also provides new data for research into the causes of several neuroinflammatory diseases and insulin resistance.
The lead author of the study is Ana María Sánchez.
The study is published in Molecular Neurobiology.
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