Healthy habits in middle age could mean longer life free from disease

In a new study, researchers found that sticking to a healthy lifestyle including not smoking, not being overweight, and exercising regularly, is linked to a longer life expectancy at age 50 free of major diseases such as cancer, heart disease, and diabetes.

The number of extra disease-free years is around 7.6 for men and 10 for women, compared with participants with no low-risk lifestyle factors.

The research was conducted by a team at the Harvard T.H. Chan School of Public Health and elsewhere.

Across the world people are, on average, living longer. But as populations age, individuals often live with disabilities and chronic diseases like cancer, heart disease, and diabetes.

Lifestyle factors such as smoking, physical activity, alcohol intake, body weight, and diet quality affect both overall life expectancy and the likelihood of chronic diseases.

But few studies have looked at how a combination of lifestyle factors may relate to life expectancy free from such diseases.

In the study, the researchers analyzed data on 73,196 US registered female nurses from the Nurses’ Health Study and 38,366 US male health professionals who were free of cancer, cardiovascular disease, and diabetes.

Five low-risk lifestyle factors—never smoking, healthy weight (BMI), at least 30 minutes of daily physical activity, moderate alcohol intake, and a good quality diet—were used to calculate a healthy lifestyle score.

The sum of these five scores together gave a final low-risk lifestyle score ranging from 0 to 5, with higher scores indicating a healthier lifestyle.

Participants were assessed regularly over a period of more than 20 years. During this time, new diagnoses and deaths from cancer, cardiovascular disease, and type 2 diabetes were recorded.

The team found life expectancy free of cancer, heart disease, and diabetes at age 50 was 24 years for women who adopted no low-risk lifestyle factors, and 34 years for women who adopted four or five low-risk factors.

Similarly, life expectancy free of any of these chronic diseases was 24 years among men who adopted no low-risk lifestyle factors and 31 years in men who adopted four or five low-risk lifestyle factors.

Women with four or five low-risk lifestyle factors had 10.6 years’ longer life expectancy free of the major chronic diseases than did women with zero low-risk lifestyle factors.

Men gained 7.6 years’ longer life expectancy free of major chronic diseases over those with zero low-risk lifestyle factors.

Men who smoked heavily (15 or more cigarettes a day) or obese men and women (body mass index of 30 or over) had the lowest proportion (75% or less) of disease-free life expectancy at age 50.

The team says public policies for improving food and the physical environment conducive to adopting a healthy diet and lifestyle, as well as relevant policies and regulations (for example, a smoking ban in public places or trans fat restrictions) are critical to improving life expectancy, especially life expectancy free of major chronic diseases.

The lead author of the study is Yanping Li from Harvard T.H. Chan School of Public Health.

The study is published in The BMJ.

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