Home Diabetes Over-the-counter supplement could prevent heart disease in type 2 diabetes

Over-the-counter supplement could prevent heart disease in type 2 diabetes

Credit: Unsplash+

Type 2 diabetes is one of the most common long-term illnesses in the world, and its effects reach far beyond blood sugar.

Over time, high sugar levels can damage blood vessels, nerves, kidneys, eyes, and especially the heart.

Many people with diabetes eventually develop heart problems because the condition changes how the body uses energy.

The heart, which needs a constant supply of energy to pump blood, can become stiff and weak when its cells are under stress.

This can slowly lead to heart failure, a serious condition in which the heart can no longer pump blood effectively. Once heart failure develops, survival rates drop sharply, making prevention extremely important.

A new study presented at a major heart conference in the United Kingdom suggests that a simple and inexpensive supplement might help protect the heart before severe damage occurs.

Researchers found that people with Type 2 diabetes who took a daily antioxidant called mitoquinone along with their usual treatment showed signs of healthier heart function after just four months. Mitoquinone is available without a prescription and is already sold as a supplement that claims to support energy and healthy aging.

Scientists have long believed that oxidative stress plays a major role in diabetic heart damage. Oxidative stress happens when harmful molecules build up inside cells and begin to damage their structures.

Antioxidants are substances that help neutralize these harmful molecules. Mitoquinone is designed to enter the energy-producing parts of cells, known as mitochondria, where much of this damage occurs. By protecting these areas, the supplement may help cells work more efficiently and reduce strain on the heart.

In the study, researchers recruited 70 adults with Type 2 diabetes who did not yet have heart disease. Half of them took a daily dose of mitoquinone in addition to their usual medications, while the other half continued with standard treatment alone.

Before and after the four-month period, the team performed detailed heart scans and tests to measure how well the heart used energy and how easily the heart muscle could relax between beats.

The results were encouraging. Those who took the supplement showed about a 15 percent improvement in how efficiently their hearts used energy while resting. Improvements were also seen during physical activity, suggesting that the heart was working more smoothly overall.

The heart muscle in the supplement group also relaxed faster after each beat, which is important because stiff heart muscle is one of the earliest signs of heart failure. These changes indicated that the early effects of diabetes on the heart had been partly reversed.

Importantly, the supplement did not appear to cause serious side effects, and none of the participants developed dangerous heart symptoms during the study.

Blood sugar control also remained stable, showing that the supplement did not interfere with standard diabetes care. The group that did not receive the supplement showed no similar improvements, suggesting that the benefits were likely linked to mitoquinone rather than chance.

Heart failure is much more common in people with diabetes than in the general population. Experts estimate that people with Type 2 diabetes are several times more likely to develop heart failure, and once diagnosed, their risk of death increases significantly.

Because of this, treatments that can protect the heart before symptoms appear could have a major impact on public health.

However, researchers caution that these findings are still preliminary. The study was relatively small and lasted only four months, which means it cannot yet prove that the supplement will prevent heart failure over the long term.

Larger studies involving more participants and longer follow-up periods are needed to confirm whether the benefits persist and whether they translate into fewer hospitalizations and deaths.

Overall, the research offers a hopeful glimpse into a possible new approach to protecting the hearts of people with diabetes. If future trials confirm the results, doctors may one day prescribe this inexpensive supplement alongside standard treatments to reduce the risk of heart failure.

The study also highlights the importance of exploring simple solutions that could improve quality of life for millions of patients.

In reviewing these findings, it is important to balance optimism with caution. The improvements in heart energy use and relaxation are promising signs, but they are early indicators rather than proof of long-term protection. Supplements can also vary in quality and may not work the same way for everyone.

Patients should not start new supplements without medical advice, especially since diabetes and heart conditions often require careful monitoring. Still, the study demonstrates how understanding the underlying causes of disease, such as energy stress in heart cells, can lead to innovative strategies for prevention.

Continued research will determine whether mitoquinone truly becomes a standard part of diabetes care or remains an experimental option.

If you care about heart health, please read studies that yogurt may help lower the death risks in heart disease, and coconut sugar could help reduce artery stiffness.

For more information about health, please see recent studies that Vitamin D deficiency can increase heart disease risk, and results showing vitamin B6 linked to lower death risk in heart disease.

Copyright © 2026 Knowridge Science Report. All rights reserved.