Scientists have made an exciting discovery that could help us live healthier lives as we grow older.
A gene called EDA2R might play a big role in the aging process, and researchers believe it could become a new target for treatments to slow down aging and reduce the risk of age-related diseases.
The study was led by Dr. Ildus Akhmetov from Liverpool John Moores University and included scientists from Italy, Switzerland, and the Netherlands. Their work was published in the journal Nature Communications.
The researchers found that EDA2R is closely connected to inflammation in the body. Inflammation is part of the body’s natural defense system, but as we age, even small amounts of inflammation can be harmful. It can slowly damage organs and tissues, leading to diseases like heart disease, diabetes, memory loss, and muscle weakness.
By studying a large database of genetic information, the team discovered that EDA2R was linked to signs of aging in many different parts of the body. They also did experiments with animals and found that when EDA2R activity increased, the animals aged faster. They had more inflammation, weaker blood vessels, and other signs of aging.
In lab tests with cells, the scientists increased the activity of EDA2R and saw that it caused harmful inflammation and poor muscle health—similar to what happens in older adults. But when they blocked the gene, these problems were less severe.
The team also studied blood samples from more than 5,000 people. They found that people with higher levels of EDA2R had more C-reactive protein (CRP) in their blood. CRP is a marker of inflammation, so this result supports the idea that EDA2R helps drive harmful inflammation as we age.
Dr. Akhmetov believes this discovery could lead to new ways to manage aging and improve health in later life. If scientists can find safe ways to reduce the activity of the EDA2R gene, they may be able to lower the risk of many age-related health problems.
The good news is that some everyday habits might already help reduce EDA2R activity. Studies have shown that staying physically active, eating fewer calories, taking the supplement ginkgo, and using the diabetes drug metformin can all help lower the gene’s levels. These are simple steps that may offer protection against the harmful effects of aging.
By better understanding EDA2R, scientists hope to create new treatments that target this gene directly. These treatments could help people stay stronger, healthier, and more active as they get older.
For those looking to reduce inflammation in the body, other research suggests that turmeric, a common spice, may help. A plant-based diet and getting enough vitamin D can also lower inflammation.
This discovery offers new hope for people who want to age in a healthier way. With more research, EDA2R could become a powerful tool in the fight against aging.
If you care about wellness, please read studies about how ultra-processed foods and red meat influence your longevity, and why seafood may boost healthy aging.
For more health information, please see recent studies that olive oil may help you live longer, and vitamin D could help lower the risk of autoimmune diseases.
Copyright © 2025 Knowridge Science Report. All rights reserved.
