High blood pressure is a health problem that affects many people. The usual way to treat it is by taking medicine every day. But more than half of the people with high blood pressure forget to take their pills regularly.
This makes it hard to control the condition. If left untreated, high blood pressure can lead to serious health issues like strokes, heart attacks, and even early death. That’s why doctors and scientists are looking for easier and better ways to help people manage it.
A new drug called zilebesiran might be a big step forward. Researchers from different places, including the University of Edinburgh, tested this new drug. They found that just one injection of zilebesiran can lower blood pressure and keep it low for up to six months.
In one study in the UK, people who got zilebesiran showed a big drop in their systolic blood pressure. This is the top number you see when your blood pressure is measured, and it shows how hard your heart is working.
Those who got a dose of 200mg or more saw their pressure drop by more than 10 points. People who received 800mg had a drop of over 20 points. This kind of drop can bring someone’s blood pressure into a much healthier range.
Zilebesiran was made by a U.S. company called Alnylam. It works by focusing on a hormone called angiotensin. This hormone makes blood vessels narrow, which raises blood pressure.
Zilebesiran stops the liver from making a protein called angiotensinogen, which is needed to create angiotensin. It does this by turning off the gene that tells the body to make the protein. This stops the process that leads to high blood pressure.
In the study, 107 people with high blood pressure took part. Out of these, 80 were given a single shot of zilebesiran, and the rest got a placebo, which is a fake treatment. The results were promising.
The researchers plan to do more studies to make sure the drug is safe and to learn more about how it works over time. Professor David Webb from the University of Edinburgh said this could be a big step forward.
It’s the first new type of drug for high blood pressure in 17 years. If proven safe and effective, zilebesiran could help people stick to their treatment without having to remember daily pills.
In the future, zilebesiran might become a simple and powerful tool to help people manage their blood pressure better. If you’re worried about high blood pressure, you may also want to learn more about lesser-known causes or lifestyle changes that can help. This drug offers real hope that managing high blood pressure can become easier and more effective.
The study was published in the New England Journal of Medicine and shows how science is moving forward to find better ways to keep us healthy.
If you care about blood pressure, please read studies about unhealthy habits that could increase high blood pressure risk, and eating eggs in a healthy diet may reduce risks of diabetes, high blood pressure.
For more information about blood pressure, please see recent studies that early time-restricted eating could help improve blood pressure, and results showing 12 foods that lower blood pressure.
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