Why common blood pressure drug may be riskier for women

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A new study from the University of Bologna has discovered something important about a common blood pressure medicine called beta-blockers.

These drugs are widely used to treat high blood pressure, but the study found that they may carry more risks for women than for men—especially for women who haven’t had heart disease before.

The research looked at over 13,000 adults from 12 countries in Europe. All of these people had high blood pressure but no history of heart problems.

The researchers wanted to know what happened when these people were admitted to the hospital with a sudden heart problem known as acute coronary syndrome, which is when the heart’s blood supply is suddenly blocked.

They found that women taking beta-blockers were almost 5% more likely to develop heart failure during their hospital stay compared to men in the same situation. That’s a worrying difference, especially since these women didn’t have heart problems before.

Heart failure is a serious condition. The study also showed that men and women who developed heart failure had a death rate that was about seven times higher than those who had a heart attack but did not develop heart failure afterward.

The problem seemed even worse for women who had a specific and dangerous type of heart attack called STEMI (ST-segment elevation myocardial infarction). In these cases, a coronary artery is completely blocked. Women in this group had a 6.1% higher chance of getting heart failure than men.

Interestingly, the study found no big difference in heart failure risk between men and women who were not taking beta-blockers. This suggests that beta-blockers may affect women differently than men.

Doctors often use beta-blockers because high blood pressure is a major risk factor for heart disease. But this study suggests that we should be more careful when prescribing them—especially for women who haven’t had heart issues before.

The researchers think one possible reason for the increased risk could be how beta-blockers interact with female hormones or hormone replacement therapy. However, more research is needed to understand this connection.

This study was led by Professor Raffaele Bugiardini and published in the journal Hypertension. It shows that medical treatments should not be one-size-fits-all. Women and men may react differently to the same medicine, and it’s important for doctors to take this into account.

For women with high blood pressure, this research is a reminder to keep a close eye on their heart health and to speak with their doctor about whether beta-blockers are the right treatment. It also shows the importance of managing blood pressure with healthy habits, like regular exercise and a balanced diet.

Overall, this study highlights the need for more personalized healthcare that looks at how gender, age, and other factors affect treatment outcomes. It could lead to better and safer ways to treat high blood pressure and prevent heart problems in the future.

If you care about blood pressure, please read studies about blood pressure drug that may increase risk of sudden cardiac arrest, and these teas could help reduce high blood pressure.

For more health information, please see recent studies about nutrient that could strongly lower high blood pressure, and results showing this novel antioxidant may help reverse blood vessels aging by 20 years.

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