Type 2 diabetes is a common health condition where the body either doesn’t use insulin properly or doesn’t make enough of it.
This leads to high levels of sugar in the blood, which can cause serious health problems over time.
The first medicine most people take for Type 2 diabetes is called metformin. It helps lower blood sugar levels and is usually very effective in the beginning. But for many people, metformin alone stops working as well after a while, and they need more help to control their blood sugar.
Researchers at Thomas Jefferson University have found a powerful combination of two other medications—dapagliflozin and exenatide—that can help. This new treatment approach not only lowers blood sugar but keeps it under control for a long time.
The study involved 695 adults with Type 2 diabetes who weren’t seeing enough improvement with metformin alone. These patients were divided into three groups.
One group took weekly injections of exenatide with metformin. Another group took daily pills of dapagliflozin with metformin. The third group received both drugs together, along with metformin.
The results showed that the group taking both dapagliflozin and exenatide had better control over their blood sugar than the groups using just one of the drugs. And importantly, this better control lasted for the full two years of the study.
Each of the drugs works in a different way. Dapagliflozin helps the kidneys get rid of extra sugar through urine. Exenatide helps the body release more insulin when you eat, reduces how much sugar the liver makes, slows digestion, and helps you feel full longer. These effects also help with weight loss and lowering blood pressure.
By combining both medications, patients get the benefits of both types of action—better blood sugar control, less weight gain, and improved blood pressure. For people who can’t manage their diabetes with metformin alone, this drug combo offers a safe and lasting solution.
The study found no unexpected side effects, which makes this combination not just effective, but also safe. The research was led by Dr. Serge Jabbour and was published in the journal Diabetes Care.
This discovery is important for people who are struggling with their blood sugar even while taking standard medications. It gives doctors and patients another option—one that works well and keeps working for years.
If you or someone you know is managing Type 2 diabetes, talk to your doctor about all the available treatments. With research like this, better care and healthier futures are within reach.
If you care about diabetes, please read studies about How to choosing the right fruits for type 2 diabetes and findings of New higher dose diabetes drug promises better blood sugar control and weight loss.
For more about diabetes, please read studies about The hidden connection between cancer and diabetes uncovered and findings of Scientists find the best way to help people with diabetes lose weight.
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