This common blood pressure drug may have unexpected health risks

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Doctors often prescribe medications to help people with high blood pressure, but researchers have found that one commonly used pill might cause unexpected problems.

The pill, called chlorthalidone, has been used for many years to lower blood pressure. However, scientists at Columbia University recently discovered that it may lead to certain side effects. They are now studying it further to learn more.

Understanding High Blood Pressure

To understand why this research matters, let’s first look at what high blood pressure is. Imagine a highway full of cars—if they start speeding too fast, accidents can happen. High blood pressure is similar; it means blood is pushing too hard against the walls of blood vessels, which can lead to serious health issues like heart attacks, strokes, and kidney disease.

The good news is that high blood pressure can be managed with medication and lifestyle changes. Doctors have been prescribing drugs like chlorthalidone and hydrochlorothiazide for years to help patients keep their blood pressure under control.

What Did the Study Find?

The researchers analyzed health data from more than 730,000 people who had taken blood pressure medication over 17 years. They compared two drugs: chlorthalidone and hydrochlorothiazide.

Both medications were effective in preventing heart attacks and strokes. However, the study found that people taking chlorthalidone were three times more likely to have low potassium levels, a condition called hypokalemia.

Why Is Potassium Important?

Potassium is an essential mineral that helps the body function properly. It plays a key role in keeping muscles and nerves working and helps maintain a healthy heartbeat.

When potassium levels drop too low, people can feel weak, tired, or even experience heart problems. According to the study, 6.3% of people taking chlorthalidone had low potassium, compared to only 1.9% of those taking hydrochlorothiazide.

Other Risks Found in the Study

Besides low potassium, researchers also found that people taking chlorthalidone were more likely to have problems with their electrolytes. Electrolytes are important chemicals in the body that help keep muscles and organs working properly, including the heart.

Additionally, the study suggested that people on chlorthalidone had a higher risk of kidney problems. Since the kidneys are responsible for filtering waste from the blood, any damage to them can lead to serious health issues.

What Does This Mean for Patients?

The study does not mean that everyone taking chlorthalidone will experience these problems. However, it does suggest that doctors should monitor patients more closely if they are using this medication.

Many doctors currently prefer prescribing chlorthalidone over hydrochlorothiazide. But after this study, they may reconsider which drug is best for their patients, especially for those at risk of low potassium or kidney issues.

How to Maintain Healthy Blood Pressure

Even if you don’t take these medications, there are many ways to keep your blood pressure under control. Some of the best strategies include:

  • Eating more fruits and vegetables and reducing salt intake
  • Exercising regularly
  • Limiting alcohol consumption
  • Quitting smoking, if applicable
  • Managing stress through activities like yoga, meditation, or simply taking a relaxing walk

What’s Next?

Scientists will continue to study chlorthalidone and other blood pressure medications to ensure they are safe and effective.

If you or someone you know is taking chlorthalidone, there’s no need to panic. The best thing to do is to have regular check-ups with your doctor and discuss any concerns you may have. Monitoring your health and staying informed is the best way to keep your blood pressure—and overall health—on the right track.

If you care about high blood pressure, please read studies that early time-restricted eating could help improve blood pressure, and natural coconut sugar could help reduce blood pressure and artery stiffness.

For more information about blood pressure, please see recent studies about How to eat your way to healthy blood pressure and results showing that Modified traditional Chinese cuisine can lower blood pressure.

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