Diabetic eye disease may strongly lower quality of life

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A research led by Mohammed G. Zayed and his team from the University of Oxford, UK, delved into the impact of diabetic retinopathy (DR) on individuals’ quality of life, particularly focusing on vision-related quality of life (VRQoL).

By conducting a systematic literature review and meta-analysis, they sought to understand how the presence and severity of this disease affect people’s daily lives.

Diabetic retinopathy, a complication of diabetes, can lead to vision impairment and, in severe cases, blindness.

It’s a condition that can significantly impact an individual’s quality of life, affecting their ability to perform daily activities, maintain employment, and enjoy social interactions.

The study analyzed data from eight studies involving a total of 1,485 participants, of whom 1,138 had DR, and 347 did not. The findings were revealing.

Using the National Eye Institute 25-item Visual Function Questionnaire (VFQ-25) to measure VRQoL, the researchers found a marked decline in scores correlating with the severity of DR.

Specifically, the VFQ-25 score was 3.8 points lower for participants with non-vision-threatening DR, 12.5 points lower for those with any level of DR, and a substantial 25.1 points lower for individuals suffering from vision-threatening DR, compared to those without DR.

Expanding their analysis to include 35 studies with 6,351 participants who had DR, the pooled mean VFQ-25 composite score further underscored the impact of DR on quality of life.

The scores averaged 91.8 for individuals with non-vision-threatening DR, dropped to 77.6 for those with any level of DR, and plummeted to 73.2 for participants with vision-threatening DR.

The research highlighted a weak or nonexistent association between health-related quality of life and non-vision-threatening DR, but a strong association was found with vision-threatening DR.

This distinction underscores the significant impact that severe DR has on an individual’s life, emphasizing the importance of early detection and intervention.

Zayed and his colleagues concluded that vision-related quality of life deteriorates with both the presence and progression of diabetic retinopathy.

Their findings advocate for interventions aimed at reducing the progression of DR at all stages, from early detection to managing more advanced conditions, to improve the quality of life for those affected by this diabetes complication.

Their work illuminates the critical need for comprehensive care strategies that not only address the medical aspects of DR but also consider the profound effects on patients’ everyday lives and well-being.

If you care about diabetes, please read studies about high vitamin D level linked to lower dementia risk in diabetes, and this eating habit could help reduce risk of type 2 diabetes.

For more information about nutrition, please see recent studies about unhealthy plant-based diets linked to metabolic syndrome, and results showing Paleo diet plus exercise could boost heart health in people with diabetes

The research findings can be found in JAMA Ophthalmology.

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