In a new study from the Deutsches Zentrum Immuntherapie, researchers examined patients who had no immune protection against the COVID-19 infection after two vaccinations (primary vaccine failure).
These people were given the third vaccination and the team found that most of them tended to develop a very good level of protection after receiving the third vaccine.
In an earlier study, the team had already demonstrated that patients with autoimmune diseases much more frequently fail to develop sufficient protection against coronavirus after two doses of the vaccine than healthy people
They found that one in ten patients with an autoimmune disease did not develop a sufficient response to the COVID vaccination, compared to one in a hundred healthy people after two doses of the vaccine.
Accordingly, patients with autoimmune diseases are particularly at risk of breakthrough infections. They were predominantly individuals with autoimmune diseases such as arthritis.
The people were among the very first to receive their booster vaccination in summer 2021.
Most of these patients who had experienced primary vaccine failure developed a robust immune response to COVID-19 after the third vaccination.
The study confirms the importance of the third vaccine.
The team says not all people are indeed “fully vaccinated” after receiving two doses of the vaccine.
As primary vaccine failure is not uncommon after two doses of a vaccine in patients with autoimmune diseases, it would make sense to check the immune status of these individuals after vaccination in order to identify any instances of primary vaccine failure promptly and prevent subsequent breakthrough infections.
If you care about COVID, please read studies about many Americans take immune-weakening drugs that may reduce COVID vaccine effects, and findings of COVID-19 vaccines need to be shored up with a plant-based diet.
For more information about the pandemic, please see recent studies about No, COVID vaccines don’t stay in your body for years, and results showing that in people who had COVID-19, Pfizer vaccine may protect against new variants.
The study is published in Annals of the Rheumatic Diseases. One author of the study is Dr. David Simon.
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