Can blood pressure drug beta-blockers increase depression risk?

Credit: Unsplash+

A major new study from the Berlin Institute of Health has brought fresh insight into how beta-blockers—a common type of heart medicine—affect mental health.

This research is important because beta-blockers are widely used to treat conditions like high blood pressure and heart disease, but many people have worried they might cause problems like depression or anxiety.

The study was published in the journal Hypertension and involved data from more than 50,000 people across 258 different studies. Many of these studies focused on people taking beta-blockers for high blood pressure. The goal was to take a close look at whether these medications really lead to mental health issues.

For years, there have been concerns that beta-blockers might be linked to depression, anxiety, or trouble sleeping. But this study found something surprising: people who took beta-blockers were not more likely to develop depression than those who took a placebo, which is a fake treatment used for comparison in studies.

In fact, the number of people who stopped taking beta-blockers because of depression was about the same as those who stopped taking other medications.

However, the researchers did find that beta-blockers might be connected to sleep problems, such as insomnia and having unusual dreams. Among all the mental health side effects they looked at, feeling tired or fatigued was the most common reason people stopped taking beta-blockers.

The overall message from the study is that beta-blockers are mostly safe when it comes to mental health. While they might cause some sleep-related issues, they do not seem to raise the risk of depression as many people once feared. This is good news for both patients and doctors.

For people taking or thinking about taking beta-blockers, this research can help ease fears about mental health side effects. It can also help doctors feel more confident when prescribing these medications, knowing they are unlikely to cause depression.

Still, it’s important for healthcare providers to pay attention to sleep-related problems in patients who are taking beta-blockers. If someone starts having trouble sleeping or feeling extra tired, it’s worth discussing with a doctor to see if any changes are needed.

This study also reminds us that treating heart disease isn’t just about physical health. Doctors and patients should also think about how medications affect mental well-being. A balanced approach that considers both the body and the mind will lead to better outcomes.

In short, this new research helps clear up old doubts about beta-blockers and depression. It shows that while sleep issues can happen, the drug is mostly safe for mental health. This allows for smarter, more informed decisions when it comes to heart care.

If you care about mental health, please read studies about how dairy foods may influence depression risk, and 6 foods you can eat to improve mental health.

For more mental health information, please see recent studies about top foods to tame your stress, and Omega-3 fats may help reduce depression.

Copyright © 2025 Knowridge Science Report. All rights reserved.