High blood pressure, also called hypertension, is a serious health issue that can quietly damage your body over time.
Many people don’t even know they have it until they suffer from something severe like a stroke, heart attack, or kidney failure. It’s like an invisible danger slowly harming your health.
But there’s some hopeful news. A new medicine called Baxdrostat might be the breakthrough people have been waiting for. This drug is especially promising for those who have tried other treatments but still have high blood pressure.
Researchers from Queen Mary University of London and CinCor Pharma in the United States have recently tested this new drug. They shared their findings at a major American Heart Association conference.
The study included 248 people who had high blood pressure that wasn’t getting better, even after trying at least three different medications. Some of the patients were given Baxdrostat, and others received a harmless placebo.
After 12 weeks, the results were amazing. The group that received the highest dose of Baxdrostat had a big drop in blood pressure — 20 points lower. This was 11 points better than the group who took the placebo. This kind of improvement is rarely seen with current medications.
What makes Baxdrostat special is how it works. It focuses on a hormone called aldosterone. This hormone helps control the salt balance in the body. When it doesn’t work properly, it can lead to high blood pressure.
The trick was to lower aldosterone without affecting another hormone called cortisol, which the body needs. The study showed that Baxdrostat successfully lowered aldosterone levels in both the blood and urine — especially in people who made too much of it.
One of the main researchers, Professor Morris Brown, said he was very excited about the results. However, he also pointed out that more testing is needed before Baxdrostat can be used widely. Even though the results look good, scientists want to be sure the drug is safe and works well over the long term.
In the UK, one in three adults has high blood pressure. Some people have a gene problem in their adrenal glands that causes them to make too much aldosterone. This leads to their bodies keeping too much salt, which raises blood pressure. Current treatments often don’t help these people enough. That’s why a drug like Baxdrostat could be a game changer.
Professor Brown has been working on this drug for over ten years. He was involved from the beginning and helped guide the trials in the U.S. His dedication shows how important this discovery could be for people with hard-to-treat high blood pressure.
Scientists are also exploring how lifestyle choices affect blood pressure. Some studies suggest eating eggs might lower your risk of both diabetes and high blood pressure. Other research shows that antioxidants may protect brain health and lower the risk of dementia. Getting more magnesium in your diet might also help your brain work better.
The promising research on Baxdrostat has been published in the New England Journal of Medicine. There’s still more work to be done, but the early signs are very hopeful.
This drug might become a powerful new tool for people who haven’t found success with other treatments. As research continues, there’s reason to feel excited about the future of treating high blood pressure.
If you care about blood pressure, please read studies about the ideal blood pressure for older people and common high blood pressure drugs may cause memory problems.
For more about blood pressure, please read studies about A common blood pressure medication that could help you live longer and 1 in 5 people with high blood pressure takes a medication that harms blood pressure.
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