A new study published in Neurology by researchers at Karolinska Institutet reveals that acute kidney injury (AKI) significantly increases the risk of developing dementia.
AKI, a sudden loss of kidney function, is common among older adults and is known for its severe impact on health. This study highlights a broader implication of AKI—its effect on brain health.
Analyzing data from the Stockholm CREAtinine Measurement (SCREAM) project, the study followed over 300,000 individuals aged 65 and older for an average of 12 years.
Around 25% experienced at least one AKI episode, and 16% were diagnosed with dementia.
Key findings include:
– A 49% higher risk of developing any form of dementia following an AKI episode.
– An 88% increased risk for Lewy body dementia or dementia associated with Parkinson’s disease.
– A 47% increased risk for vascular dementia.
– A 31% increased risk for Alzheimer’s disease.
– The risk was higher for patients with severe AKI requiring hospitalization.
The study suggests that AKI could have lasting effects on brain function, emphasizing the importance of early intervention and long-term care for those who suffer from AKI.
Future research will focus on understanding the biological mechanisms behind this association and evaluating strategies to mitigate dementia risk post-AKI.
If you care about kidney health, please read studies about pesticide linked to chronic kidney disease, and this drug may prevent kidney failure in people with diabetes.
For more health information, please see recent studies about drug duo that may treat kidney failure, and results showing these vegetables may protect against kidney damage.
The study is published in Neurology.
Copyright © 2025 Knowridge Science Report. All rights reserved.
