Some diabetes drugs may raise heart disease risk

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Type 2 diabetes is a growing health issue. It happens when the body can’t use insulin properly, leading to high blood sugar levels.

Doctors usually start treatment with a medicine called metformin. But if metformin isn’t enough, other drugs are added.

A new study from Northwestern University has found that two common diabetes drugs might raise the risk of heart problems. This could be important for patients and doctors when choosing the best treatment plan.

The study looked at six second-line drugs often given to people with type 2 diabetes. Researchers found that two of these—sulfonylureas and basal insulin—were linked to a higher risk of heart disease. Compared to a newer type of drug called DPP-4 inhibitors, sulfonylureas raised the heart risk by 36%, while basal insulin doubled the risk.

Because of these findings, the researchers suggest doctors may want to use newer drugs like GLP-1 agonists, SGLT-2 inhibitors, or DPP-4 inhibitors instead. These medications are more expensive, but they appear to be safer for the heart and could reduce hospital visits caused by serious heart issues.

This study is important because it raises questions about the safety of some commonly used diabetes drugs. But it also has some limits. The study used real-world data and wasn’t a controlled lab experiment. It didn’t compare how well each drug lowers blood sugar, and it didn’t look into whether certain patients might still do well on the older drugs.

Even so, the results are worth thinking about. If you have type 2 diabetes, it’s a good idea to learn about the possible effects of your medications. Some drugs could put extra stress on your heart. That’s why it’s important to talk openly with your doctor about the benefits and risks of different treatment options.

Choosing a treatment plan for diabetes isn’t just about controlling blood sugar. It’s also about protecting your heart and overall health. Newer drugs may cost more, but they could help prevent bigger problems down the road.

Besides medication, a healthy lifestyle can make a big difference. Regular exercise, eating a balanced diet, keeping a healthy weight, quitting smoking, getting enough sleep, and managing stress are all key to staying well with diabetes.

Taking care of your heart is a big part of managing type 2 diabetes. With the right choices, you can live a longer and healthier life.

If you care about heart health, please read studies about top 10 foods for a healthy heart, and how to eat right for heart rhythm disorders.

For more health information, please see recent studies about how to eat your way to cleaner arteries, and salt and heart health: does less really mean more?

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