A new study from the University of Pittsburgh has found that how tired an older person feels after everyday activities can help predict their risk of dying within the next few years. The research shows that people who report high levels of fatigue are more than twice as likely to die within 2.7 years compared to those who feel less tired.
This study, led by Dr. Nancy W. Glynn and published in The Journals of Gerontology: Series A, looked at the connection between “fatigability”—how tired someone feels or expects to feel after doing common tasks—and early death.
While past studies have shown that physical activity can help reduce fatigue, this is the first time researchers have linked higher levels of fatigability to a shorter lifespan.
To measure this, the team used a tool called the Pittsburgh Fatigability Scale, which was created in 2014. The scale asks people how tired they think they would feel after certain activities, such as a 30-minute slow walk, light house cleaning, or heavy gardening.
The participants rate their expected fatigue levels from 0 (not at all tired) to 5 (extremely tired) for each activity. The total score shows how physically fatigable a person feels.
The researchers tested 2,906 adults aged 60 and older who were part of the Long-Life Family Study, a project that looks at aging and health in families known for their longevity. Participants filled out the fatigability scale, and their health was tracked over the next few years.
The results showed a clear pattern: people who scored 25 or higher on the scale were 2.3 times more likely to die within the next 2.7 years compared to those who scored lower than 25. This connection held true even after researchers accounted for other health factors that could affect mortality, such as existing diseases or physical limitations.
This finding suggests that feeling easily tired, even just thinking about doing activities, may be an early warning sign of declining health. Fatigue might reflect deeper problems in the body, such as reduced heart or lung function, poor muscle strength, or other changes that come with aging.
Importantly, the Pittsburgh Fatigability Scale is simple to use and has been translated into 11 languages. This means it could be used around the world to help doctors identify older adults who may be at higher risk of health decline—even before serious symptoms appear.
The researchers say their study also highlights the importance of helping older adults stay physically active. Regular movement can lower feelings of fatigue and improve overall health, which may lead to longer and better-quality lives.
For people who are aging or caring for older loved ones, paying attention to how tired they feel after common tasks—or how tired they expect to feel—could provide helpful insight into their overall health and longevity.
If you care about wellness, please read studies about nutrients that could combat inflammation in older people, and essential foods for healthy aging.
For more health information, please see recent studies about the link between processed foods and chronic diseases, and a simple diet change for a healthier life after 65.
Copyright © 2025 Knowridge Science Report. All rights reserved.
